Association of physical activity with physical function and quality of life in people with hip and knee osteoarthritis: longitudinal analysis of a population-based cohort

Arthritis Research & Therapy

Research

Eduardo B. Cruz¹  David G. Lopes²  Nuno Mendonça²  Ana Rita Henriques²  Helena Canhão²  Jaime Branco³  Daniela Costa⁴  Ana M. Rodrigues⁵ 

[1] Comprehensive Health Research Centre (CHRC), NOVA Medical School

[2]  Faculdade de Ciências Médicas, NMS

[3] FCM, Universidade Nova de Lisboa, Lisbon, Portugal;Physiotherapy Department, School of Health, Polytechnic Institute of Setúbal, Setúbal, Portugal;EpiDoC Unit, NOVA Medical School

[4] FCM, Universidade Nova de Lisboa, Edifício Amarelo, Rua Do Instituto Bacteriológico, nº5, 1150-082, Lisbon, Portugal;Comprehensive Health Research Centre (CHRC), NOVA Medical School

[5] FCM, Universidade Nova de Lisboa, Lisbon, Portugal;EpiDoC Unit, NOVA Medical School

[6] FCM, Universidade Nova de Lisboa, Lisbon, Portugal;Centro Hospitalar Lisboa Ocidental (CHLO-E.P.E.), Serviço de Reumatologia Do Hospital Egas Moniz, Lisbon, Portugal;EpiDoC Unit, NOVA Medical School

[7] FCM, Universidade Nova de Lisboa, Lisbon, Portugal;NOVA National School of Public Health, Public Health Research Centre, Universidade Nova de Lisboa, Lisbon, Portugal;EpiDoC Unit, NOVA Medical School

[8] FCM, Universidade Nova de Lisboa, Lisbon, Portugal;Rheumatology Unit, Hospital Dos Lusíadas, Lisbon, Portugal;

关键词: Osteoarthritis;    Health-related quality of life;    Physical function;    Exercise;    Longitudinal;   

DOI  :  10.1186/s13075-023-02996-x

 received in 2022-09-09, accepted in 2023-01-19,  发布年份 2023

来源: Springer

【 摘 要 】

Hip and knee osteoarthritis (HKOA) is a chronic disease characterized by joint pain that leads to reduced physical function and health-related quality of life (HRQoL). At present, no cure is available. Clinical trials indicate that people with HKOA benefit from physical activity in several health-related outcomes. However, few studies have evaluated the long-term positive effect of regular physical activity. This study analyzed participants with HKOA from a nationwide population-based cohort (EpiDoC Cohort) to assess the impact of physical activity on patients’ physical function and HRQoL over a long-term follow-up. The regular weekly frequency of intentional physical activity was self-reported as non-frequent (0 times/week), frequent (1–2 times/week), or very frequent (≥ 3 times/week). This study followed 1086 participants over a mean period of 4.7 ± 3.4 years, during which 6.3% and 14.9% of participants reported frequent and very frequent physical activity, respectively. Using linear mixed models, we found that frequent (β =  − 0.101 [− 0.187, − 0.016]; β = 0.039 [− 0.002, 0.080]) and very frequent physical activity (β =  − 0.061 [− 0.118, − 0.004]; β = 0.057 [0.029, 0.084]) were associated with improved physical function and HRQoL over time, respectively, when compared with non-frequent exercise, adjusting for years to baseline, sex, age, years of education, body mass index, multimorbidity, hospitalizations, clinical severity, and unmanageable pain levels. These findings raise awareness of the importance of maintaining exercise/physical activity long term to optimize HRQoL and physical function. Further studies must address barriers and facilitators to improve the adoption of regular physical activity among citizens with HKOA.

【 授权许可】

CC BY   
© The Author(s) 2023

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