期刊论文详细信息
Diagnostic Pathology | |
NK/T-cell lymphoma with rash and peripheral neuropathy as the first manifestation: a case report and literature review | |
Review | |
Zizhu Tian1  Jing Tian2  Jiafen Liao2  | |
[1]Department of Hematology, the Second Xiangya Hospital, Central South University, 410011, Changsha, Hunan, China | |
[2]Department of Rheumatology and Immunology, the Second Xiangya Hospital, Central South University, 410011, Changsha, Hunan, China | |
关键词: ENKTCL-NT; Peripheral neuropathy; CD30 positive; EBV infection; Hemophagocytic syndrome; | |
DOI : 10.1186/s13000-023-01286-z | |
received in 2022-10-29, accepted in 2023-01-03, 发布年份 2023 | |
来源: Springer | |
【 摘 要 】
BackgroundExtranodal NK/T-cell lymphoma, nasal type (ENKTCL-NT), is a rare, aggressive subtype of non-Hodgkin lymphoma, and it usually presents as a destructive sinus mass that may attend epistaxis. However, ENKTCL-NT with the manifestation of peripheral neuropathy is pretty unusual.Case presentationA 17-year-old Chinese patient presented with peripheral neuropathy and positive auto-antibodies. However, she failed methylprednisolone pulse therapy and developed hemophagocytic syndrome. The diagnosis of CD30-positive primary cutaneous ENKTCL-NT was confirmed by pathological biopsy. Her disease was brought under control after five cycles of chemotherapy.ConclusionsThe report findings are helpful in the differential diagnosis of peripheral neuropathy and autoimmune disease. We should be alert for the development of ENKTCL-NT when the rash and peripheral neuropathy are the first symptoms and are accompanied by Epstein-Barr virus (EBV) infection.【 授权许可】
CC BY
© The Author(s) 2023
【 预 览 】
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RO202305111960186ZK.pdf | 1578KB | download | |
41116_2022_35_Article_IEq99.gif | 1KB | Image | download |
Fig. 1 | 128KB | Image | download |
Fig. 13 | 114KB | Image | download |
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