Prevalence of depression and anxiety, and their relationship to social support among patients and family caregivers of rare bone diseases

Orphanet Journal of Rare Diseases

Research

Xuefeng Lai¹  Shengfeng Wang¹  Zhijun Zhang²  Yue Sun²  Yuling Jiang³ 

[1] Department of Epidemiology and Biostatistics, School of Public Health, Peking University, 38 Xueyuan Road, Haidian District, 100191, Beijing, China;Lingyi Foundation for Rare Bone Diseases, 1A801, Gaofa West Bund Garden, 5th Avenue, Anbao District, 518133, Shenzhen, China;School of Public Health, Peking University, 38 Xueyuan Road, Haidian District, 100191, Beijing, China;

关键词: Rare bone diseases;    Depression;    Anxiety;    Social support;   

DOI  :  10.1186/s13023-022-02611-3

 received in 2022-06-01, accepted in 2022-12-29,  发布年份 2022

来源: Springer

【 摘 要 】

BackgroundRare bone diseases (RBDs) are a set of inherited rare diseases that can cause disability and have a devastating impact on families affected, which may lead to a particular high prevalence of psychological disorders in patients and caregivers. Social support plays a role in the well-being of families with rare disease patients, but its effect on psychology of RBD families remains unclear. The purpose of the current cross-sectional quantitative study was to investigate the frequency of depression and anxiety, and their relationship with social support among RBD patients and family caregivers.ResultsA total of 196 participants responded to the questionnaire, including 72 patients and 124 caregivers. Depression was detected among 33.8% of patients and 57% of caregivers, and anxiety disorder was presented in 28.6% of patients and 50% of caregivers. Higher depression scores and anxiety scores were found in both patients and caregivers with an education level of ≤ middle school and monthly income of ≤ ￥2000 (all P < 0.05). The mean (SD) scores of Social Support Rating Scales in patients and caregivers were 37.06 (8.05) and 38.31 (5.76), respectively. After adjusting for gender, age, monthly income, education, employment and marital status, the reverse associations between depression scores, anxiety scores and social support were found merely in caregivers (depression & social support: β = − 0. 46, P < 0.001, anxiety & social support: β = − 0. 44, P < 0.001), specifically for subjective support (depression & subjective support: β = − 0.94, P < 0.001, anxiety & subjective support: β = − 0.87, P < 0.001).ConclusionsThe study identified a high prevalence of depression and anxiety among RBD patients and caregivers, and pointed out the significance of social support in alleviating psychological distress. In order to provide RBD families with comprehensive assistance, the government should actively develop programs aimed at psychological aid, policy advocacy and tangible support.

【 授权许可】

CC BY   
© The Author(s) 2023

【 图 表 】

Fig. 4