Improvement of sleep quality in isolated metastatic patients with spinal cord compression after surgery

World Journal of Surgical Oncology

Research

Mengqiu Deng¹  Yue Yu²  Cheng Peng³  Shuang Cao³  Chengzhang Zhu³  Tielong Liu³  Xin Gao³  Jianjun Chu⁴  Baoquan Xin⁵ 

[1] Department of Anesthesiology, Changzheng Hospital, Naval Medical University, Shanghai, China;Department of Anesthesiology, Chaohu Hospital of Anhui Medical University, Hefei, Anhui Province, China;Department of Orthopedics, Changzheng Hospital, Naval Medical University, Shanghai, China;Department of Orthopedics, the Second People’s Hospital of Hefei, Hefei, Anhui Province, China;School of Health Science and Engineering, University of Shanghai for Science and Technology, Shanghai, China;

关键词: Quality of sleep;    Isolated spinal metastasis;    Metastatic spinal cord compression;    Total en bloc spondylectomy;    Palliative surgery with stereotactic radiosurgery;   

DOI  :  10.1186/s12957-023-02895-0

 received in 2022-10-17, accepted in 2023-01-10,  发布年份 2023

来源: Springer

【 摘 要 】

BackgroundThis study aimed to assess changes in quality of sleep (QoS) in isolated metastatic patients with spinal cord compression following two different surgical treatments and identify potential contributing factors associated with QoS improvement.MethodsWe reviewed 49 patients with isolated spinal metastasis at our spinal tumor center between December 2017 and May 2021. Total en bloc spondylectomy (TES) and palliative surgery with postoperative stereotactic radiosurgery (PSRS) were performed on 26 and 23 patients, respectively. We employed univariate and multivariate analyses to identify the potential prognostic factors affecting QoS.ResultsThe total Pittsburgh Sleep Quality Index (PSQI) score improved significantly 6 months after surgery. Univariate analysis indicated that age, pain worsening at night, decrease in visual analog scale (VAS), increase in Eastern Cooperative Oncology Group performance score (ECOG-PS), artificial implant in focus, and decrease in epidural spinal cord compression (ESCC) scale values were potential contributing factors for QoS. Multivariate analysis indicated that the ESCC scale score decreased as an independent prognostic factor.ConclusionsPatients with spinal cord compression caused by the metastatic disease had significantly improved QoS after TES and PSRS treatment. Moreover, a decrease in ESCC scale value of > 1 was identified as a favorable contributing factor associated with PSQI improvement. In addition, TES and PSRS can prevent recurrence by achieving efficient local tumor control to improve indirect sleep. Accordingly, timely and effective surgical decompression and recurrence control are critical for improving sleep quality.

【 授权许可】

CC BY   
© The Author(s) 2023

【 图 表 】

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