Hemodiafiltration combined with polymyxin B-immobilized fiber column direct hemoperfusion is effective for acute postoperative exacerbation of interstitial pneumonia: a case report

JA Clinical Reports

Case Report

Takahiro Tamura¹  Koshiro Kikkawa²  Ryohei Ito²  Tatsuro Yokoyama³  Morihide Ando⁴  Harunori Nakashima⁴ 

[1] Department of Anesthesiology, Nagoya University Graduate School of Medicine, Nagoya, Japan;Department of Anesthesiology, Ogaki Municipal Hospital, Ogaki, Japan;Department of Anesthesiology, Ogaki Municipal Hospital, Ogaki, Japan;Department of Anesthesiology, Nagoya University Graduate School of Medicine, Nagoya, Japan;Department of Respiratory Medicine, Ogaki Municipal Hospital, Ogaki, Japan;

关键词: Blood purification therapy;    Interstitial pneumonia;    Acute exacerbation;    Extracorporeal membrane oxygenation;    ECMO;    Respiratory failure;    Rheumatoid arthritis;   

DOI  :  10.1186/s40981-022-00589-2

 received in 2022-10-13, accepted in 2022-12-19,  发布年份 2022

来源: Springer

【 摘 要 】

BackgroundPostoperative acute exacerbation of interstitial pneumonia has a high mortality rate; however, its treatment methods have not been standardized.Case presentationA 72-year-old man with rheumatoid arthritis developed acute respiratory failure about 3 weeks after lung cancer surgery. There were increased diffuse frosted shadows in both lung fields. His condition was diagnosed as an acute exacerbation of interstitial pneumonia associated with rheumatoid arthritis, and he was started on steroid pulse therapy; however, his respiratory condition deteriorated. He was urgently intubated and started on veno-venous extracorporeal membrane oxygenation. Further, intensive care, including blood purification therapy, was initiated. The blood purification therapy comprised a combination of hemodiafiltration and 6-h polymyxin B-immobilized fiber column direct hemoperfusion. The patient was weaned off veno-venous extracorporeal membrane oxygenation, extubated, and discharged from the intensive care unit on the ninth day.ConclusionsBlood purification therapy was effective for acute exacerbation of interstitial pneumonia.

【 授权许可】

CC BY   
© The Author(s) 2022

【 图 表 】

Fig. 1

12888_2022_4322_Article_IEq1.gif