Toxico-clinical study of patients poisoned with household products; a two-year cross-sectional study

BMC Pharmacology and Toxicology

Research

Sara Niknam¹  Nastaran Eizadi-Mood²  Sahar Sadat Lalehzar³  Rokhsareh Meamar³  Razieh Mahvari³  Parisa Mirmoghtadaee³ 

[1] Clinical Biochemistry Research Center, Shahrekord University of Medical Sciences, Shahrekord, Iran;Department of Clinical Toxicology, School of Medicine, Isfahan Clinical Toxicology Research Center, Isfahan University of Medical Sciences, Isfahan, Iran;Isfahan Clinical Toxicology Research Center, Isfahan University of Medical Sciences, Isfahan, Iran;

关键词: Poisoning;    Household products;    Corrosive substances;    Hydrocarbons;    Outcome;   

DOI  :  10.1186/s40360-022-00640-z

 received in 2022-04-11, accepted in 2022-12-19,  发布年份 2022

来源: Springer

【 摘 要 】

BackgroundSeveral studies worldwide have investigated household product poisoning. We conducted a toxico-clinical study on the two-year prevalence of poisoning with household products.MethodsThis cross-sectional study was performed in Khorshid Hospital, the main referral center for poisoning cases in Isfahan, affiliated to Isfahan University of Medical Sciences, Isfahan, central Iran. All patients with intentional or unintentional household substance poisoning, referring to the poisoning emergency center of the hospital, were evaluated with respect to epidemiological and toxico-clinical features and outcomes.ResultsDuring the study period, 5946 patients were hospitalized, of which 83 (1.39%) had been poisoned with household products including 48 (57.8%) men and 35 (42.2%) women with a mean ± SD age of 34.40 ± 17.71 years. Most patients (54.2%) were in the 20–40-year-old age group. Accidental poisoning (63.9%) was the most common type of exposure (P = 0.02) predominantly in men (57.8%, P = 0.51). The most common household products were sodium hypochlorite (32.53%) followed by petroleum hydrocarbon (21.68%). Most of the accidental poisonings (77.8%) were due to petroleum hydrocarbon. 59% of cases were poisoned at home (P < 0.0001). No patient died.ConclusionHousehold products were not common means of poisoning in our referral center. Sodium hypochlorite and petroleum hydrocarbon were the most common substances. Most of the patients were men with accidental exposure at home. Because of the availability of the household product, the frequency and outcomes may be varied in different societies.

【 授权许可】

CC BY   
© The Author(s) 2022

【 图 表 】

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