Longitudinal profiling in patients undergoing cardiac surgery reveals postoperative changes in DNA methylation

Clinical Epigenetics

Research

Tristan Grogan¹  Hua Cai¹  Matthew A. Fischer¹  Douglas J. Chapski¹  Elizabeth Soehalim¹  Thomas M. Vondriska²  Matteo Pellegrini³  Dennis J. Montoya³  Richard J. Shemin⁴ 

[1] Department of Anesthesiology & Perioperative Medicine, David Geffen School of Medicine, UCLA, CHS 37-100, 650 Charles Young Dr, 90095, Los Angeles, CA, USA;Department of Anesthesiology & Perioperative Medicine, David Geffen School of Medicine, UCLA, CHS 37-100, 650 Charles Young Dr, 90095, Los Angeles, CA, USA;Department of Medicine, David Geffen School of Medicine, UCLA, Los Angeles, USA;Department of Physiology, David Geffen School of Medicine, UCLA, Los Angeles, USA;Department of Molecular, Cellular & Developmental Biology, David Geffen School of Medicine, UCLA, Los Angeles, USA;Department of Surgery, David Geffen School of Medicine, UCLA, Los Angeles, USA;

关键词: DNA methylation;    Cardiac surgery;    Precision medicine;    Atrial fibrillation;   

DOI  :  10.1186/s13148-022-01414-4

 received in 2022-10-17, accepted in 2022-12-18,  发布年份 2022

来源: Springer

【 授权许可】

CC BY   
© The Author(s) 2022

【 图 表 】

Fig. 1

Fig. 6

12982_2022_119_Article_IEq153.gif

12982_2022_119_Article_IEq152.gif

12888_2022_4365_Article_IEq54.gif

12888_2022_4365_Article_IEq52.gif

12888_2022_4365_Article_IEq50.gif