Breath-by-breath P0.1 measured on quasi-occlusion via Hamilton C6 may result in underestimation of respiratory drive and inspiratory effort

Critical Care

Brief Report

Muneyuki Takeuchi¹  Maki Miwa²  Ryo Takane²  Richard H. Kaszynski²  Tomotsugu Nakano²  Mikio Nakajima²  Hideaki Goto² 

[1] Department of Intensive Care Medicine, Osaka Women’s and Children’s Hospital, Osaka, Japan;Emergency and Critical Care Center, Tokyo Metropolitan Hiroo Hospital, 2−34−10, Ebisu, Shibuya-Ku, 150-0013, Tokyo, Japan;

关键词: P0.1;    Esophageal pressure;    Occlusion pressure;    Swing;    Respiratory drive;    Inspiratory effort;    COVID-19;    Mechanical ventilation;   

DOI  :  10.1186/s13054-022-04286-5

 received in 2022-09-07, accepted in 2022-12-17,  发布年份 2022

来源: Springer

【 摘 要 】

We aimed to identify the threshold for P0.1 in a breath-by-breath manner measured by the Hamilton C6 on quasi-occlusion for high respiratory drive and inspiratory effort. In this prospective observational study, we analyzed the relationships between airway P0.1 on quasi-occlusion and esophageal pressure (esophageal P0.1 and esophageal pressure swing). We also conducted a linear regression analysis and derived the threshold of airway P0.1 on quasi-occlusion for high respiratory drive and inspiratory effort. We found that airway P0.1 measured on quasi-occlusion had a strong positive correlation with esophageal P0.1 measured on quasi-occlusion and esophageal pressure swing, respectively. Additionally, the P0.1 threshold for high respiratory drive and inspiratory effort were calculated at approximately 1.0 cmH2O from the regression equations. Our calculations suggest a lower threshold of airway P0.1 measured by the Hamilton C6 on quasi-occlusion than that which has been previously reported.

【 授权许可】

CC BY   
© The Author(s) 2022

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