Pre-neuromusculoskeletal injury Risk factor Evaluation and Post-neuromusculoskeletal injury Assessment for Return-to-duty/activity Enhancement (PREPARE) in military service members: a prospective, observational study protocol

Journal of Translational Medicine

Protocol

Daniel I. Brooks¹  Matthew B. Garber²  Donald L. Goss³  Nora L. Watson⁴  Alisha D. Harvey⁵  Courtney M. Butowicz⁶  Brad D. Hendershot⁶  Timothy C. Mauntel⁷  Matthew S. Helton⁸  Robert A. Whitehurst⁸  Joseph R. Kardouni⁸ 

[1] Clinical Quality Management, Defense Health Agency, 7700 Arlington Blfd, 22042, Falls Church, VA, USA;Department of Health, Human Function and Rehabilitation Science, The George Washington University, 2200 Pennsylvania Ave NW, 20006, Washington, DC, USA;Department of Physical Therapy, High Point University, 1 N University Pkwy, 27268, High Point, NC, USA;Department of Research, Walter Reed National Military Medical Center, 4494 Palmer Rd N, 20814, Bethesda, MD, USA;Physical Therapy Service, Department of Rehabilitation, Walter Reed National Military Medical Center, 4494 Palmer Rd N, 20814, Bethesda, MD, USA;Research & Surveillance Division, Extremity Trauma and Amputation Center of Excellence, 4494 Palmer Rd N, 20814, Bethesda, MD, USA;Research & Development Section, Department of Rehabilitation, Walter Reed National Military Medical Center, 4494 Palmer Rd N, 20814, Bethesda, MD, USA;Department of Physical Medicine & Rehabilitation, Uniformed Services University of the Health Sciences, 4301 Jones Bridge Rd, 20814, Bethesda, MD, USA;Research & Surveillance Divsion, Extremity Trauma & Amputation Center of Excellence, 2817 Reilly Rd, 28310, Fort Bragg, NC, USA;Department of Surgery, Uniformed Services University of the Health Sciences, 4301 Jones Bridge Rd, 20814, Bethesda, MD, USA;Department of Clinical Investigations, Womack Army Medical Center, 2817 Reilly Rd, 28301, Fort Bragg, NC, USA;U.S. Army Forces Command, 4700 Knox St, 28301, Fort Bragg, NC, USA;

关键词: Musculoskeletal injury;    Neuromuscular;    Military;    Service member;    Tactical athlete;    Risk assessment;    Risk mitigation;   

DOI  :  10.1186/s12967-022-03832-7

 received in 2022-05-25, accepted in 2022-12-14,  发布年份 2022

来源: Springer

【 摘 要 】

BackgroundNon-battle related musculoskeletal injuries (MSKI) are one of the primary medical issues diminishing Service member medical readiness. The MSKI problem is challenging because it is difficult to assess all of the factors that increase MSKI risk and influence post-MSKI outcomes. Currently, there are no high-throughput, clinically-feasible, and comprehensive assessments to generate patient-centric data for informing pre- and post-MSKI risk assessment and mitigation strategies. The objective of the “Pre-neuromusculoskeletal injury Risk factor Evaluation and Post-neuromusculoskeletal injury Assessment for Return-to-duty/activity Enhancement (PREPARE)” study is to develop a comprehensive suite of clinical assessments to identify the patient-specific factors contributing to MSKI risks and undesired post-MSKI outcomes.MethodsThis is a phased approach, multi-center prospective, observational study (ClinicalTrials.gov number: NCT05111925) to identify physical and psychosocial factors contributing to greater MSKI risk and undesired post-MSKI outcomes, and to identify and validate a minimal set of assessments to personalize risk mitigation and rehabilitation strategies. In Phase I, one cohort (n = 560) will identify the physical and psychosocial factors contributing to greater MSKI risks (single assessment), while a second cohort (n = 780) will identify the post-MSKI physical and psychosocial factors contributing to undesired post-MSKI outcomes (serial assessments at enrollment, 4 weeks post-enrollment, 12 weeks post-enrollment). All participants will complete comprehensive movement assessments captured via a semi-automated markerless motion capture system and instrumented walkway, joint range of motion assessments, psychosocial measures, and self-reported physical fitness performance and MSKI history. We will follow participants for 6 months. We will identify the minimum set of clinical assessments that provide requisite data to personalize MSKI risk mitigation and rehabilitation strategies, and in Phase II validate our optimized assessments in new cohorts.DiscussionThe results of this investigation will provide clinically relevant data to efficiently inform MSKI risk mitigation and rehabilitation programs, thereby helping to advance medical care and retain Service members on active duty status.Trial Registration: PREPARE was prospectively registered on ClinicalTrials.gov (NCT05111925) on 5 NOV 2021, prior to study commencement.

【 授权许可】

CC BY   
© This is a U.S. Government work and not under copyright protection in the US; foreign copyright protection may apply 2022

【 图 表 】

Fig. 1