Effectiveness of seasonal influenza vaccine in elementary and middle schools: a 10-year follow-up investigation

BMC Infectious Diseases

Research Article

Etsushi Akimoto¹  Ikuo Kanazawa²  Akiko Kato³  Sumera Mukai⁴  Teruyuki Kajiume⁵  Toshio Shirakawa⁶  Nobutaka Toyota⁷ 

[1] Hiroshima Akichiku Medical Association, 5-13 Sakae-machi, Kaita-cho, Aki-gun, 736-0043, Hiroshima, Japan;Akimoto Clinic, 3-34 Inari-machi, Kaita-cho, Aki-gun, 736-0067, Hiroshima, Japan;Hiroshima Akichiku Medical Association, 5-13 Sakae-machi, Kaita-cho, Aki-gun, 736-0043, Hiroshima, Japan;Kanazawa Cardiology Clinic, 4-10-18 Yano-nishi, Aki-ku, 736-0085, Hiroshima, Japan;Hiroshima Akichiku Medical Association, 5-13 Sakae-machi, Kaita-cho, Aki-gun, 736-0043, Hiroshima, Japan;Kato Gastroenterology Clinic, 3-3-14 Nakano-higashi, Aki-ku, 739-0323, Hiroshima, Japan;Hiroshima Akichiku Medical Association, 5-13 Sakae-machi, Kaita-cho, Aki-gun, 736-0043, Hiroshima, Japan;Mukai Clinic of Internal Medicine, 2-2-8 Tahara, Ondo-cho, 737-1216, Kure-city, Hiroshima, Japan;Hiroshima Akichiku Medical Association, 5-13 Sakae-machi, Kaita-cho, Aki-gun, 736-0043, Hiroshima, Japan;Mukainada Child Clinic, 24-26 Aosaki-naka, Fuchu-cho, Aki-gun, 735-0016, Hiroshima, Japan;Hiroshima Akichiku Medical Association, 5-13 Sakae-machi, Kaita-cho, Aki-gun, 736-0043, Hiroshima, Japan;Senosirakawa Hospital, 1-28-3 Seno, Aki-ku, 739-0311, Hiroshima, Japan;Hiroshima Akichiku Medical Association, 5-13 Sakae-machi, Kaita-cho, Aki-gun, 736-0043, Hiroshima, Japan;Toyota Ladies Clinic, 4-30-1 Kawasumi, Kumano-cho, Aki-gun, 731-4223, Hiroshima, Japan;

关键词: Follow-up studies;    Surveys and questionnaires;    Influenza vaccines;    Immunization;    Infection;   

DOI  :  10.1186/s12879-022-07898-y

 received in 2022-05-04, accepted in 2022-11-25,  发布年份 2022

来源: Springer

【 摘 要 】

BackgroundInfluenza spreads from schools to the rest of society. Thus, we conducted questionnaire surveys of influenza vaccination in elementary and middle schools in a district for 10 years to determine immunization rates and infection conditions among students who were potential sources of infection at home.MethodsThe questionnaire-based survey on influenza vaccine administration, influenza infection, and influenza types contracted, as well as influenza immunization history, was conducted in 10 seasons over a period of 10 years.ResultsIn elementary schools, vaccination was associated with lower morbidity in most years, whereas in middle schools, morbidity increased among students who were vaccinated every year. Our study did not find consistent trends among faculty and staff. In addition, we found that morbidity was significantly higher among elementary (P < 0.001) and middle (P < 0.05) school students who had been vaccinated since infancy than among those who had not been vaccinated since infancy.ConclusionsThe results of this study suggest that vaccinating infants for influenza may increase the risk of contracting influenza later in life.

【 授权许可】

CC BY   
© The Author(s) 2022

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