Neutralizing and enhancing antibodies against SARS-CoV-2

Inflammation and Regeneration

Review

Yafei Liu¹  Hisashi Arase¹ 

[1] Department of Immunochemistry, Research Institute for Microbial Diseases, Osaka University, 565-0871, Osaka, Japan;Laboratory of Immunochemistry, WPI Immunology Frontier Research Center, Osaka University, 565-0871, Osaka, Japan;

关键词: SARS-CoV-2;    Neutralizing antibody;    Enhancing antibody;   

DOI  :  10.1186/s41232-022-00233-7

 received in 2022-09-23, accepted in 2022-10-30,  发布年份 2022

来源: Springer

【 摘 要 】

The high transmissibility and rapid global spread of SARS-CoV-2 since 2019 has led to a huge burden on healthcare worldwide. Anti-SARS-CoV-2 neutralizing antibodies play an important role in not only protecting against infection but also in clearing the virus and are essential to providing long-term immunity. On the other hand, antibodies against the virus are not always protective. With the emergence of SARS-CoV-2 immune escape variants, vaccine design strategies as well as antibody-mediated therapeutic approaches have become more important. We review some of the findings on SARS-CoV-2 antibodies, focusing on both basic research and clinical applications.

【 授权许可】

CC BY   
© The Author(s) 2022

【 图 表 】

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