Do prescription rates of psychotropic drugs change over three years from nursing home admission?

BMC Geriatrics

Research

Geir Selbæk¹  Cato Grønnerød²  Jūratė Šaltytė Benth³  Sverre Bergh⁴  Enrico Callegari⁵ 

[1] Faculty of Medicine, University of Oslo, Oslo, Norway;Norwegian National Advisory Unit on Ageing and Health, Vestfold Hospital Trust, Tønsberg, Norway;Department of Geriatric Medicine, Oslo University Hospital, Oslo, Norway;Faculty of Social Sciences, Department of Psychology, University of Oslo, Oslo, Norway;Østfold Hospital Trust, Sykehuset Østfold HF, postboks 300, 1714, Grålum, Norway;Institute of Clinical Medicine, Campus Ahus, University of Oslo, Oslo, Norway;Research Centre for Age-related Functional Decline and Diseases, Innlandet Hospital Trust, Ottestad, Norway;Health Services Research Unit, Akershus University Hospital, Lørenskog, Norway;Research Centre for Age-related Functional Decline and Diseases, Innlandet Hospital Trust, Ottestad, Norway;Norwegian National Advisory Unit on Ageing and Health, Vestfold Hospital Trust, Tønsberg, Norway;Østfold Hospital Trust, Sykehuset Østfold HF, postboks 300, 1714, Grålum, Norway;Faculty of Medicine, University of Oslo, Oslo, Norway;

关键词: Geriatric pharmacotherapy;    Psychotropic drugs;    Nursing homes;   

DOI  :  10.1186/s12877-021-02437-x

 received in 2021-03-11, accepted in 2021-08-26,  发布年份 2021

来源: Springer

【 摘 要 】

BackgroundIn this longitudinal study, we describe how psychotropic drugs (PTDs) are prescribed in nursing home (NH) patients from admission and over a 3-year period, to understand which clinical and environmental factors are associated with PTD prescription.MethodsWe used data from the Resource Use and Disease Course in Dementia – Nursing Home (REDIC-NH) study, examining physical and mental health, dementia, and PTD prescription during a 3-year period from admission to a NH. Data were collected every six months. At baseline, we included 696 participants from 47 Norwegian NHs. We presented prevalence, incidence, and deprescribing rates of PTD prescriptions for each assessment point. We calculated the odds of receiving PTDs and used a generalized linear mixed model to analyze the variables associated with a change in odds throughout the 3-year period.ResultsPTD prescriptions were frequent throughout the 3-year period. Antidepressants had the highest prescription rates (28.4%–42.2%). Every PTD category had the highest incidence rate between admission and six months, and antidepressants had the highest values (18.9%). Deprescribing rates were generally highest between baseline and 6-months follow-up, except for sedatives and hypnotics. The odds of antipsychotic prescriptions were lower for older people (OR = 0.96, 95%CI:0.92–0.99, p = 0.023). People with more severe dementia had lower odds of being prescribed sedatives/hypnotics (OR = 0.89, 95%CI:0.85–0.94, p < 0.001).ConclusionsPTDs, particularly antidepressants, are widely prescribed over time to NH patients. Older patients are less likely to receive antipsychotics. A higher severity of dementia decreases the odds of being prescribed sedatives/hypnotics. Close attention should be paid to PTD prescriptions during long-term NH stay to avoid prolonged and excessive treatment with these types of drugs.Trial registrationClinicalTrials.gov Identifier: NCT01920100.

【 授权许可】

CC BY   
© The Author(s) 2021. corrected publication 2022

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