Development and evaluation of a novel dietary bisphenol A (BPA) exposure risk tool

BMC Nutrition

Research Article

Joseph Rigdon¹  Roy S. Zawadzki²  Jennifer C. Hartle³  Christopher D. Gardner⁴  Juleen Lam⁵ 

[1] Department of Biostatistics and Data Science, Wake Forest School of Medicine, 27157, Winston-Salem, NC, USA;Department of Biostatistics, California Polytechnic State University-San Luis Obispo, 94307, San Luis Obispo, CA, USA;Department of Statistics, Donald Bren School of Information and Computer Sciences, University of California, 92697, Irvine, CA, USA;Department of Public Health and Recreation, San José State University, 95192, San José, CA, USA;Stanford Prevention Research Center, Stanford University School of Medicine, 94305, Stanford, CA, USA;University of California at San Francisco, 94107, San Francisco, CA, USA;California State University East Bay, 94542, Hayward, CA, USA;

关键词: Bisphenol A;    Food packaging;    Environmental phenols;    Diet;    Exposure;    Risk;    Questionnaire;   

DOI  :  10.1186/s40795-022-00634-4

 received in 2021-11-16, accepted in 2022-11-05,  发布年份 2022

来源: Springer

【 摘 要 】

BackgroundExposure to endocrine disrupting chemicals such as bisphenol A (BPA) is primarily from the diet through canned foods. Characterizing dietary exposures can be conducted through biomonitoring and dietary surveys; however, these methods can be time-consuming and challenging to implement.MethodsWe developed a novel dietary exposure risk questionnaire to evaluate BPA exposure and compared these results to 24-hr dietary recall data from participants (n = 404) of the Diet Intervention Examining The Factors Interacting with Treatment Success (DIETFITS) study, a dietary clinical trial, to validate questionnaire responses. High BPA exposure foods were identified from the dietary recalls and used to estimate BPA exposure. Linear regression models estimated the association between exposure to BPA and questionnaire responses. A composite risk score was developed to summarize questionnaire responses.ResultsIn questionnaire data, 65% of participants ate canned food every week. A composite exposure score validated that the dietary exposure risk questionnaire captured increasing BPA exposure. In the linear regression models, utilizing questionnaire responses vs. 24-hr dietary recall data, participants eating canned foods 1–2 times/week (vs. never) consumed 0.78 more servings (p < 0.001) of high BPA exposure foods, and those eating canned foods 3+ times/week (vs. never) consumed 0.89 more servings (p = 0.013) of high BPA exposure foods. Participants eating 3+ packaged items/day (vs. never) consumed 62.65 more total grams of high BPA exposure food (p = 0.036).ConclusionsDietary exposure risk questionnaires may provide an efficient alternative approach to 24-hour dietary recalls to quantify dietary BPA exposure with low participant burden.Trial registrationThe trial was prospectively registered at clinicaltrials.gov as NCT01826591 on April 8, 2013.

【 授权许可】

CC BY   
© The Author(s) 2022

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