Tuberculosis treatment outcomes among pulmonary TB patients attending public hospitals in Kebbi State, Northern Nigeria: a four-year retrospective study

Bulletin of the National Research Centre

Research

Yahaya Tajjudeen¹  Musa Mohammed²  Bashar Haruna Gulumbe³  Abbas Yusuf Bazata³  Mohammed Bashar Danlami³  Aliyu Basiru³ 

[1] Department of Biological Sciences, Faculty of Sciences, Federal University Birnin Kebbi, P.M.B. 1157, Kalgo, Nigeria;Department of Medical Laboratory Science, Kebbi State College of Health Science and Technology, P.M.B. 9003, Jega, Kebbi State, Nigeria;Department of Microbiology, Faculty of Sciences, Federal University Birnin Kebbi, P.M.B. 1157, Kalgo, Nigeria;

关键词: Successful outcome;    Treatment outcome;    Pulmonary tuberculosis;    Kebbi;    Nigeria;   

DOI  :  10.1186/s42269-022-00969-9

 received in 2022-10-21, accepted in 2022-12-08,  发布年份 2022

来源: Springer

【 摘 要 】

BackgroundIn Nigeria, effective case management and evaluation of pulmonary tuberculosis treatment outcomes are an integral part of controlling the spread of infectious diseases. The study reviewed the treatment outcomes of pulmonary tuberculosis and the factors associated with rates of successful and unsuccessful treatment outcomes in the 21 referral hospitals in Kebbi State, Nigeria.MethodsDocumented records of pulmonary tuberculosis patients from January 2018 to December 2021 in 21 Local Area Councils in Kebbi State, Northern Nigeria were reviewed. A structured questionnaire collated the socio-demographic and clinical data from the documented records. Descriptive statistics were used to compute and analyse the outcomes of successful and unsuccessful treatment. Logistic regression models were used to determine the association of socio-demographic and clinical data with the unsuccessful treatment outcomes.ResultsThe study reviewed data from 6114 records of TB patients. 1161 (18.9%) started treatment, 963 (82.9%) were males and 198 (17.1%) were females. Of the 1161 patients, 985 (18.2%) had documented treatment outcomes. 932 of 985 (95.1%) had a pulmonary infection. 64 (5.8%) patients with documented treatment outcomes were HIV seropositive. 903 (91.7%) were successfully treated, and 82 (8.3%) failed. Of the patients with failed treatment outcomes, 15 (1.5%) were lost to follow-up, 43 (4.4%) defaulted and 24 (2.4%) died. In the logistic analysis, the odds of unsuccessful treatment outcomes were higher among elderly patients (AOR = 2.00, 95% CI 1.37–2.92), patients with extrapulmonary infections (AOR = 2.40, 95% CI 1.12–5.39), and with old cases of pulmonary TB (AOR = 3.03, 95% CI 1.47–7.19) when compared to their groups.ConclusionsThe study reported a treatment success rate of 91.7% among TB patients attending public hospitals in Kebbi State. The outcome was higher than the projected success rate of 85% set by the WHO. However, one-fourth of the total patients reviewed were not documented for treatment. Therefore, the need to design an appropriate recruitment strategy to identify and enrol those patients for an effective and successful TB control program in Nigeria.

【 授权许可】

CC BY   
© The Author(s) 2022