Relationship between red blood cell distribution width-to-albumin ratio and outcome of septic patients with atrial fibrillation: a retrospective cohort study

BMC Cardiovascular Disorders

Research

Zai-shen Dai¹  Yan Chen¹  You-lan Gu¹  Duo Yang²  Zhi-bin Huang³ 

[1] Department of Anesthesiology, Guangzhou Panyu Maternal Child Health Hospital (Guangzhou Panyu District He Xian Memorial Hospital), No. 2 Qinghe East Road, Shiqiao Street, 511400, Guangzhou, China;Department of Anesthesiology, Jieyang People’s Hospital, NO.107 Tianfu Road, Rongcheng street, 522000, Jieyang, China;Department of Anesthesiology, Maoming People’s Hospital, No.101 Weimin Road, Maonan street, 525000, Maoming, China;

关键词: Red blood cell distribution width;    Albumin;    Atrial fibrillation;    Sepsis;    Retrospective cohort study;    MIMIC-IV;   

DOI  :  10.1186/s12872-022-02975-1

 received in 2022-08-08, accepted in 2022-11-23,  发布年份 2022

来源: Springer

【 摘 要 】

BackgroundThis retrospective cohort study aimed to investigate the association between red blood cell distribution width-to-albumin ratio (RAR) and in-hospital mortality in patients with sepsis and atrial fibrillation (AF).MethodsData were obtained from the Medical Information Mart for the Intensive Care Database IV database version 1.0. Multivariate Cox regression models, curve-fitting, and Kaplan–Meier analyses were performed to determine the correlation between RAR and in-hospital mortality in patients with sepsis and AF.ResultsThis study included 3042 patients with sepsis and AF. Confounding variables were adjusted for in the Multivariable Cox regression analysis models. RAR was independently associated with in-hospital mortality (hazard ratio 1.06; 95% confidence interval 1.03–1.08; p < 0.001). A linear relationship was found between the RAR and in-hospital mortality in patients with sepsis and AF.ConclusionElevated RAR levels are associated with increased in-hospital mortality in patients with sepsis and AF. Further research is required to confirm this association.

【 授权许可】

CC BY   
© The Author(s) 2022

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