COVID-19 vaccination side effects among the child age group: a large cross-sectional online based survey in Saudi Arabia

BMC Infectious Diseases

Research

Abdallah Y. Naser¹  Emad Salawati²  Hamza Assaggaf³  Faisal Minshawi³  Mohammed Almatrafi⁴  Jaber S. Alqahtani⁵  Areen Naif Alosaimi⁶  Zaid Majeed⁶  Mohammed Samannodi⁶  Safaa Mohammed Alsanosi⁶  Ahmad Alhazmi⁶  Rasha Abdulaziz Mandili⁶  Hassan Alwafi⁷  Abdulelah M. Aldhahir⁸  Rakan Ekram⁹ 

[1] Department of Applied Pharmaceutical Sciences and Clinical Pharmacy, Faculty of Pharmacy, Isra University, Amman, Jordan;Department of Family Medicine, Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia;Department of Laboratory Medicine, Faculty of Applied Medical Sciences, Umm Al-Qura University, Mecca, Saudi Arabia;Department of Pediatrics, Faculty of Medicine, Umm Al-Qura University, Mecca, Saudi Arabia;Department of Respiratory Care, Prince Sultan Military College of Health Sciences, Dammām, Saudi Arabia;Faculty of Medicine, Umm Al-Qura University, Mecca, Saudi Arabia;Faculty of Medicine, Umm Al-Qura University, Mecca, Saudi Arabia;Al-Noor Specialist Hospital, Mecca, Saudi Arabia;Respiratory Therapy Department, Faculty of Applied Medical Sciences, Jazan University, Jazan, Saudi Arabia;School of Public Health and Health Informatics, Umm Al-Qura University, Mecca, Saudi Arabia;

关键词: COVID-19;    Vaccination;    Side effects;    Children;    Saudi Arabia;   

DOI  :  10.1186/s12879-022-07905-2

 received in 2022-08-11, accepted in 2022-11-29,  发布年份 2022

来源: Springer

【 摘 要 】

BackgroundMultiple vaccines have been tested in clinical trials for their efficacy and safety. In Saudi Arabia, Pfizer–BioNTech or Moderna were approved for children, however, previous studies to report their safety profile are limited. This research aims to understand the side effect of children's vaccination against SARS-CoV-2 infection in Saudi Arabia.MethodsThis was an observational retrospective cross-sectional study was conducted using an online survey in Saudi Arabia from March to May 2022. The inclusion criteria were parents aged 18 years and above who live in Saudi Arabia and have vaccinated their children. The self-reported questionnaire was adopted from published studies to investigate the study objectives Descriptive statistics were used to describe patients’ demographic characteristics, continuous data were reported as mean ± S.D., categorical data were reported as percentages (frequencies), and logistic regression was used to identify predictors of persistent post-COVID-19 symptoms.ResultsThis study had a total of 4,069 participants. Only 41.9% of the participants reported that their child(ren) had been infected with the coronavirus. 2.00 was the median number of children (IQR: 1.00–4.00). More than half of the study participants (64.2%) reported that a family member had been infected with the coronavirus. Both parents received COVID-19 vaccination, according to most participants (88.7%). Most participants (70.5%) stated that all children who met the vaccination criteria had received the vaccine. Most participants (83.5%) said their child or children had two doses of their vaccine, and about half (50.4%) of those who received the vaccine reported experiencing side effects. In addition, the majority (78.9%) reported that the side effects appeared within one day of receiving the vaccine, and nearly two-thirds (65.7%) reported that the side effects lasted between one and three. A total of 11,831 side effects cases were documented. Pain at the injection site, hyperthermia, and fatigue were the most reported side effects, accounting for 15.3%, 14.1%, and 13.2%, respectively.ConclusionIt appears that the side effects of the COVID-19 vaccine for children are minor, tolerable, and like those described previously in clinical trials. Our data should encourage the public about the safety of receiving the COVID-19 vaccine for children.

【 授权许可】

CC BY   
© The Author(s) 2022

【 图 表 】

Fig. 2