Ginsenoside Rg1 inhibits nucleus pulposus cell apoptosis, inflammation and extracellular matrix degradation via the YAP1/TAZ pathway in rats with intervertebral disc degeneration

Journal of Orthopaedic Surgery and Research

Research Article

Hong Hu¹  Xiao-peng Gu¹  Shao-jin Zhong²  Xiang-lian Wan³  Bin Hu⁴  Yong-hua Yang⁴  Zhi-ping Gu⁴ 

[1] Department of Orthopaedics, Zhoushan Guhechuan Bone Injury Hospital, 316101, Zhoushan,, Zhejiang, China;Pharmaceutical Department, Orthopedics and Diabetes Hospital in Haikou, Shanghai Sixth People’s Hospital, 570311, Haikou, Hainan, China;Pharmaceutical Department, Affiliated Haikou Hospital of Xiangya Medical College, Central South University, 570208, Haikou, Hainan, China;The Nursing Department, Jiujiang First People’s Hospital, 332000, Jiujiang, Jiangxi, China;The Third Department of Orthopedics, Jiujiang First People’s Hospital, 332000, Jiujiang, Jiangxi, China;

关键词: Intervertebral disc degeneration;    Nucleus pulposus cells;    Ginsenoside Rg1;    YAP1/TAZ signaling pathway;   

DOI  :  10.1186/s13018-022-03443-4

 received in 2022-10-28, accepted in 2022-12-07,  发布年份 2022

来源: Springer

【 授权许可】

CC BY   
© The Author(s) 2022

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