Paradoxes of breast cancer incidence and mortality in two corners of Europe

BMC Cancer

卷:22

Research

Dimitra Sifaki-Pistolla¹  Georgia Velivasaki¹  Mikaela Roginski²  Åshild Faresjö²  Andreas Stomby²  Tomas Faresjö²  Christos Lionis³ 

[1] Clinic of Social and Family Medicine, Faculty of Medicine, University of Crete, Heraklion, Greece;

[2] Department of Health, Medicine and Caring Sciences, Linköping University, SE-581 83, Linköping, Sweden;

[3] Department of Health, Medicine and Caring Sciences, Linköping University, SE-581 83, Linköping, Sweden;Clinic of Social and Family Medicine, Faculty of Medicine, University of Crete, Heraklion, Greece;

关键词: Breast cancer;    Comparative study;    Incidence;    Mortality;    Register data;   

DOI  :  10.1186/s12885-022-10243-w

 received in 2022-06-01, accepted in 2022-10-27,  发布年份 2022

来源: Springer

【 摘 要 】

BackgroundBreast cancer incidence is rising globally, while mortality rates show a geographical heterogenous pattern. Early detection and treatment have been proven to have a profound impact on breast cancer prognosis. The aim of his study was to compare breast cancer incidence, mortality, and survival rates in two contrasting corners of Europe, Sweden and Crete, to better understand cancer determinants with focus on disease burden and sociocultural factors.MethodsBreast cancer data from Sweden and Crete was derived from registries. Incidence and mortality were expressed as Age-Standardized Incidence Rates (ASIR), Age-Standardized Mortality Rates (ASMR).FindingsBreast cancer incidence has for decades risen in Sweden and on Crete. In 2019, ASIR was 217.5 in Sweden and 58.9 on Crete, (p < 0.001). Mortality rates showed opposite trends. ASMR in Sweden was reduced from 25.5 to 16.8 (2005-2019) while on Crete, ASMR increased from 22.1 to 25.3. A successive rise in survival rate in Sweden with a 5-year survival rate of 92% since 2015, but a converse development on Crete with 85% 5-year survival rate the same year.InterpretationThe incidence of breast cancer is slowly rising in both studied regions, but mortality increases on Crete in contrast to Sweden with sinking mortality rates. The interpretation of these findings is that differences in health care systems and health policies including differences in early detection like screening programs and early treatment, as well as sociocultural factors in the two countries might play an important role on the differences found in breast cancer burden.

【 授权许可】

CC BY   
© The Author(s) 2022

【 图 表 】

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