Chemometric-Based Optimization of Ionic Liquid-Based Dispersive Liquid-Liquid Microextraction for Separation and Preconcentration of Erythrosine from Real Matrices

npj Clean Water

article

Adil ELİK¹  Nail ALTUNAY² 

[1] Cumhuriyet Üniversitesi;CUMHURIYET UNIVERSITY

关键词: Chemometric optimization;    Erythrosine;    Ionic liquid;    Microextraction;    Real matrices.;   

DOI  :  10.17776/csj.1007785

学科分类：社会科学、人文和艺术（综合）

来源: Springer

【 摘 要 】

In this research paper, a simple and economic ionic liquid-based liquid-liquid microextraction (IL-DLLME)procedure was developed to ensure efficient and rapid separation and preconcentration of erythrosine fromcosmetic and food samples. Important parameters such as IL volume, temperature, acetone volume, ultrasonictime and pH that may affect the IL-DLLME procedure have been optimized by central composite design (CCD)based on response surface methodology (RSM). The optimum values of IL volume, temperature, acetonevolume, ultrasonic time and pH were determined as 440 µL, 35 oC, 120 µL, 9 min and 4.2, respectively. Usingthese optimum conditions, some analytical data obtained for erythrosine were listed below. Working range,limit of detection and enrichment factor were 2-400 ng mL-1, 0.65 ng mL-1 and 79, respectively. The relativestandard deviation (RSD%) was 2.4% for 50 ng mL-1 of erythrosine. The recovery obtained in the analysis of realsamples was in the range of 93.2-108.5%. The analytical data obtained showed that the IL-DLLME procedure wassuccessfully applied to the selected samples.

【 授权许可】

CC BY