Click Reactivity of Azide-Modified PolyvinylChloride as an Entry to Glycopolymer Scaffolds

Croatica Chemica Acta

article

Ay, Emriye¹  Yenil, Nilgün¹ 

[1] Manisa Celal Bayar University, Sciences & Arts Faculty, Department of Chemistry, Muradiye Campus

关键词: protected-sugar alkynes;    PVC-N3;    click reactions;    1;    2;    3-triazole.;   

DOI  :  10.5562/cca3883

学科分类：化学（综合）

来源: Croatica Chemica Acta

【 摘 要 】

We report the synthesis of new carbohydrate/triazole polymers based on poly(viny chloride) (PVC). Azide incorporation intocommercially available PVC was carried out using nucleophilic substitution and Cu-catalyzed reaction of the resulting PVC-N3 using three alkynylcontaining acetonide-protected monosaccharides (based on D-glucose and D-galactose) provided a set of PVC-based polymers incorporating atriazolyl linkage with monosaccharide moieties present on the periphery. Modified polymers were characterized by using Fourier transforminfrared (FT-IR), Nuclear Magnetic Resonance (1H-NMR and 13C-NMR) spectroscopy, together with thermogravimetric and surfacemorphological analysis.

【 授权许可】

CC BY