Recurrent pituitary apoplexy due to two successive neoplasms presenting with ocular paresis and epistaxis

Endocrinology, Diabetes & Metabolism Case Reports

article

Stephanie Teasdale¹  Fahid Hashem¹  Sarah Olson¹  Benjamin Ong¹  Warrick J Inder¹ 

[1] Princess Alexandra Hospital;School of Medicine, The University of Queensland

关键词: Geriatric;    Male;    White;    Australia;    Pituitary;    Pituitary;    Cortisol;    Glucocorticoids;    Testosterone;    FSH;    LH;    TSH;    Thyroxine (T4);    Triiodothyronine (T3);    GH;    IGF1;    Prolactin;    Pituitary apoplexy;    Pituitary haemorrhage;    Pituitary tumour (malignant);    Sixth nerve palsy;    Epistaxis;    Headache;    Nausea;    Vomiting;    Ptosis;    Diplopia;    Hemianopia;    Bitemporal hemianopia;    Visual disturbance;    Hypogonadism;    Hypoprolactinaemia;    Cortisol (serum);    Testosterone;    FSH;    LH;    TSH;    FT3;    FT4;    GH;    IGF1;    Prolactin;    Histopathology;    Visual field assessment;    MRI;    Haemoglobin;    CT;    Transsphenoidal surgery;    Radiotherapy;    Thyroxine;    Testosterone;    Cortisone;    Oncology;    Ophthalmology;    Otolaryngology;    Unique/unexpected symptoms or presentations of a disease;    February;    2015;   

DOI  :  10.1530/EDM-14-0088

学科分类：血液学

来源: Bioscientifica Ltd.

【 摘 要 】

A case of recurrent pituitary apoplexy is described in a 72-year-old man who initially presented with haemorrhage in a nonfunctioning pituitary adenoma. Five years later, he re-presented with a severe pituitary haemorrhage in an enlarging sellarmass invading both cavernous sinuses causing epistaxis and bilateral ocular paresis. Subsequent histology was consistent witha sellar malignant spindle and round cell neoplasm. Multiple pituitary tumours have previously been reported to coexist inthe same individual, but to our knowledge this is the only case where two pathologically distinct pituitary neoplasms havesequentially arisen in a single patient. This case is also notable with respect to the progressive ocular paresis, includingbilateral abducens nerve palsies, and the presentation with epistaxis.

【 授权许可】

CC BY-NC-ND