Stress cardiomyopathy (Takotsubo) following radioactive iodine therapy

Endocrinology, Diabetes & Metabolism Case Reports

article

Anastasia Dimakopoulou¹  Karunakaran Vithian²  David Gannon²  Allan Harkness² 

[1] Whittington Hospital;Colchester Hospital University NHS Foundation Trust

关键词: Adult;    Female;    White;    United Kingdom;    Heart;    Thyroid;    Thyroid;    TSH;    Thyroxine (T4);    Graves' disease;    Takotsubo cardiomyopathy;    Thyrotoxicosis;    Hyperthyroidism;    Thyroiditis;    Goitre (multinodular);    Heart failure;    Tachycardia;    Sweating;    Lips - dry;    Dyspnoea;    Angiography;    Electrocardiogram;    Echocardiogram;    TSH;    Thyroid function;    FT4;    FT3;    Troponin;    Chest auscultation;    Radionuclide therapy;    Radioiodine;    Carbimazole;    Prednisolone;    Glucocorticoids;    Ramipril;    Carvedilol;    Alpha-blockers;    Propylthiouracil;    Levothyroxine;    Cardiology;    Unusual effects of medical treatment;    August;    2015;   

DOI  :  10.1530/EDM-15-0053

学科分类：血液学

来源: Bioscientifica Ltd.

【 摘 要 】

A 55-year-old female patient presented to the endocrine clinic with Grave’s disease. She was initially treated withcarbimazole. After an early relapse, a decision was made to proceed with radioactive iodine therapy. Four days afterradioiodine administration, she presented to the emergency department with chest tightness and dyspnea due to heartfailure. Biochemistry revealed thyrotoxicosis and significantly elevated Troponin-T. There was ST segment elevation onelectrocardiography. However, coronary angiography was normal. Ventricular function was fully restored after 6 weeksof supportive medical management. A diagnosis of stress cardiomyopathy following radioactive iodine therapy was made.This is the second case reported in the literature so far to the best of our knowledge.

【 授权许可】

CC BY-NC-ND