Rare association of insulin autoimmune syndrome with ankylosing spondylitis

Endocrinology, Diabetes & Metabolism Case Reports

article

Nishant Raizada¹  S H Rahaman¹  D Kandasamy²  V P Jyotsna¹ 

[1] Departments of Endocrinology and Metabolism, All India Institute of Medical Sciences;Departments of Radiology, All India Institute of Medical Sciences

关键词: Adult;    Male;    Asian - Indian;    India;    Pancreas;    Diabetes;    Insulin;    Insulin autoimmune syndrome;    Arthritis;    Autoimmune disorders;    Hyperinsulinaemia;    Hypoglycaemia;    Sweating;    Palpitations;    Acanthosis nigricans;    Erythrocyte sedimentation rate;    Glucose (blood;    fasting);    Glucose (blood);    Insulin;    Glucose tolerance (oral);    MRI;    Serum free insulin;    Bound insulin;    Anti-insulin antibodies;    Diet;    Novel diagnostic procedure;    October;    2015;   

DOI  :  10.1530/EDM-15-0090

学科分类：血液学

来源: Bioscientifica Ltd.

【 摘 要 】

Insulin autoimmune syndrome (IAS) is a rare cause of hyperinsulinemic hypoglycaemia, which is known to occur inassociation with the use of sulfhydryl-containing drugs and autoimmune disorders. We describe a patient with hitherto anunreported association of IAS with ankylosing spondylitis. We have also performed and described a simplified method ofpolyethylene glycol (PEG) precipitation of an insulin bound antibody in the serum.

【 授权许可】

CC BY-NC-ND