Relationship between thyroid disorder and iron deficiency anaemia in pregnancy

New Indian Journal of OBGYN

article

Mili D. Chowdhury¹  S.S. Ghose¹  Abhish Mohan¹ 

[1] Department of Surgery, Naval Hospital Powai

关键词: Thyroid disorders;    iron;    antenatal;    anaemia;    hypothyroidism;    hyperthyroidism.;   

DOI  :  10.21276/obgyn.2021.7.2.10

学科分类：社会科学、人文和艺术（综合）

来源: Barpeta Obstetrics and Gynaecological Society

【 摘 要 】

Background: Thyroid disorders and iron deficiency (ID) are associated with obstetrical and fetal complications. Ironis essential for the normal functioning of thyroid peroxidase (TPO-abs) and ID is frequent during pregnancy.Objective: The present study was undertaken to see the relationship between iron deficiency anaemia and thyroiddisorder in antenatal cases. Methods: A total of 100 cases attending the outpatient department of Obstetrics andGynecology in their 1st trimester (from LMP to 12 weeks) were studied at Naval Hospital Powai during a period fromJan 2016 to Dec 2017. A detailed clinical and obstetric history was taken and patients were subjected to routineantenatal investigations along with thyroid profile. Results: Among 100 cases, 21 antenatal cases had increased TSH.Out of which 4 cases had overt hypothyroidism and 17 cases had subclinical hypothyroidism. 2 cases had decreasedthyroid stimulating hormone in early trimester out of which only 1 had overt hyperthyroidism. In the same study 23cases had mild iron deficiency anaemia and 4 had moderate anaemia. It was later correlated that out of 27 cases withanaemia 14 had hypothyroidism. 51% of the cases with anaemia had hypothyroidism and 60% of the hypothyroidcases had iron deficiency anaemia. Applying regression analysis between TSH and Hb level, there was a positivecorrelation between these two factors in cases. r2value was found to be 0.2871. This was statistically significant witha P value of less than 0.005. Conclusion: It is concluded that there is increased prevalence of thyroid disorders andiron deficiency anaemia in antenatal cases and there is relationship between iron deficiency anaemia and hypothyroidcases.

【 授权许可】

CC BY-NC-SA