期刊论文详细信息
Annals of Ayurvedic Medicine | |
Chyawanprash as add on to the standard of care in preventing COVID-19 infection among apparently healthy health care workers A single arm, longitudinal study | |
article | |
Nitin Jindal1  Shivshankar Rajput2  Babita Yadav3  Pallavi Mundada3  Richa Singhal3  Shalini Varshney1  Kiran Nimbalkar1  Rakesh Rana3  Shruti Khanduri3  BCS Rao3  Shweta Mata4  Bharti5  Narayanam Srikanth3  R.K. Manchanda6  Kartar Singh Dhiman3  | |
[1]A and U Tibbia College and Hospital | |
[2]Central Ayurveda Research Institute, Central Council for Research in Ayurvedic Sciences CCRAS | |
[3]Central Council for Research in Ayurvedic Sciences | |
[4]Central Ayurveda Research | |
[5]Central Ayurveda Research Institute | |
[6]Directorate of AYUSH | |
关键词: Ayurveda; Prophylactic; Rasayana; SARS-CoV-2; | |
DOI : 10.5455/AAM.73639 | |
学科分类:医学(综合) | |
来源: Association of Ayurvedic Physicians of India | |
![]() |
【 摘 要 】
Objective: To assess the efficacy and safety of Chyawanprash in preventing SARS-CoV-2 infection among health carepersonnel working at COVID-19 isolation ward.Setting: A hospital designated as COVID-19 care centre in Delhi, IndiaParticipants: Apparently healthy health care workers (HCWs) of age 20 to 60 years who were RT PCR negative andasymptomatic but possibly had exposure to active cases of COVID- 19, with or without co-morbid conditions were included.Pregnant and lactating females, volunteers with malignancy, uncontrolled blood sugar, chronic renal failure, chronic heartfailure, hematological disorders, and those on immunosuppressants were excluded from the study.Interventions: Chyawanprash, an Ayurvedic rasayana medicine 12 gm orally with warm water twice daily for 30 days alongwith standard preventive measures adopted by the institute. Primary Outcome: Incidence of COVID-19 infection confirmedby RT-PCR test. Secondary Outcomes: Evaluation of safety of the study drug through hematological & biochemicalinvestigations and occurrence of any adverse drug reaction or adverse events; number of participants developing any otherbacterial, viral or fungal infection during the study period and changes in inflammatory and immune markers.Results: At the end of study period, out of total 50 participants enrolled, two were COVID -19 positive. Incidence rate insimilar population in the same study setting prior to commencing (9.71%) and after completing the study period (1.79%) wascompared with incidence of COVID-19 during treatment period (1.09%). So, Chyawanprash showed protection rate of98.91%. It was well tolerated by all the study participants, when administered for 30 days.Conclusions: The infection rate at the hospital dropped significantly following administration of Chyawanprash. AsChyawanprash shows potential of a prophylactic agent against infection by SARS-CoV-2 infection, and is safe when usedin the recommended daily dosage, a randomized controlled trial to prove its prophylactic efficacy can be designed on largersample size.【 授权许可】
CC BY-NC-SA
【 预 览 】
Files | Size | Format | View |
---|---|---|---|
RO202303290003273ZK.pdf | 2013KB | ![]() |