Sleep-disordered breathing in pregnancy and glucose metabolism: is earlier detection better?

Sleep

article

Pamidi, Sushmita¹  Kalyani, Rita R²  Pien, Grace W³ 

[1] Department of Medicine, Division of Respiratory Medicine, McGill University Health Centre;Department of Medicine, Division of Endocrinology, Diabetes, and Metabolism, Johns Hopkins University School of Medicine;Department of Medicine, Division of Pulmonary and Critical Care Medicine, Johns Hopkins University School of Medicine

DOI  :  10.1093/sleep/zsac014

学科分类：生理学

来源: American Academy of Sleep Medicine

【 摘 要 】

In the past decade, published literature has demonstrated theimportant relationship of sleep-disordered breathing (SDB) tothe development of gestational diabetes mellitus (GDM) in latepregnancy. The prevalence estimates for GDM range between10% and 25% of pregnancies in different regions worldwide [1].GDM is defined as diabetes that is diagnosed for the first timeduring pregnancy, usually in the second or third trimester (24–28 weeks) based on a screening oral glucose tolerance test, inwomen without known pregestational diabetes. Women withGDM have a greater risk of birth complications, including spontaneous abortion, fetal anomalies, macrosomia, higher ratesof cesarian section, and a 10-fold increased risk of developingtype 2 diabetes later in life compared to women without GDM.Offspring of mothers with GDM also have an increased risk ofdeveloping obesity and type 2 diabetes.

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