Video-polysomnography procedures for diagnosis of rapid eye movement sleep behavior disorder (RBD) and the identification of its prodromal stages: guidelines from the International RBD Study Group

Sleep

article

Cesari, Matteo¹  Heidbreder, Anna¹  St. Louis, Erik K²  Sixel-Döring, Friederike⁴  Bliwise, Donald L⁶  Baldelli, Luca⁷  Bes, Frederik⁸  Fantini, Maria Livia⁹  Iranzo, Alex^1,10  Knudsen-Heier, Stine^1,11  Mayer, Geert⁵  McCarter, Stuart²  Nepozitek, Jiri^1,13  Pavlova, Milena^1,14  Provini, Federica⁷  Santamaria, Joan^1,10  Sunwoo, Jun-Sang^1,16  Videnovic, Aleksandar^1,17  Högl, Birgit¹  Jennum, Poul^1,18  Christensen, Julie A E^1,18  Stefani, Ambra¹ 

[1] Department of Neurology, Medical University of Innsbruck;Mayo Center for Sleep Medicine, Departments of Neurology and Medicine, Division of Pulmonary and Critical Care Medicine, Mayo Clinic College of Medicine and Science;Department of Research, Mayo Clinic Health System Southwest Wisconsin;Paracelsus Elena Klinik;Department of Neurology, Philipps-University;Sleep Center, Department of Neurology, Emory University School of Medicine;Department of Biomedical and Neuromotor Sciences, University of Bologna;Clinic for Sleep- and Chronomedicine;NPsy-Sydo, Clermont-Ferrand University Hospital, Neurology Department, Université Clermont Auvergne;Sleep Disorders Center, Neurology Service, Hospital Clínic Barcelona, Universitat de Barcelona;Norwegian Center of Expertise for Neurodevelopmental Disorders and Hypersomnias ,(NevSom), Department of Rare disorders, Oslo University Hospital;Department of Neurology;Department of Neurology and Center of Clinical Neuroscience, First Faculty of Medicine, Charles University, General University Hospital;Department of Neurology, Brigham and Women’s Hospital, Division of Sleep Medicine, Harvard Medical School;IRCCS, Istituto delle Scienze Neurologiche di Bologna;Department of Neurosurgery, Seoul National University Hospital;Department of Neurology, Massachusetts General Hospital, Harvard Medical School;Danish Center for Sleep Medicine, Department of Clinical Neurophysiology, Rigshospitalet Glostrup;Department of Health Technology, Technical University of Denmark

关键词: IRBDSG;    iRBD;    RWA;    iRWA;    prodromal RBD;    PSG;   

DOI  :  10.1093/sleep/zsab257

学科分类：生理学

来源: American Academy of Sleep Medicine

【 摘 要 】

Video-polysomnography (v-PSG) is essential for diagnosing rapid eye movement (REM) sleep behavior disorder (RBD). Although there are current American Academy of Sleep Medicine standards to diagnose RBD, several aspects need to be addressed to achieve harmonization across sleep centers. Prodromal RBD is a stage in which symptoms and signs of evolving RBD are present, but do not yet meet established diagnostic criteria for RBD. However, the boundary between prodromal and definite RBD is still unclear. As a common effort of the Neurophysiology Working Group of the International RBD Study Group, this manuscript addresses the need for comprehensive and unambiguous v-PSG recommendations to diagnose RBD and identify prodromal RBD. These include: (1) standardized v-PSG technical settings; (2) specific considerations for REM sleep scoring; (3) harmonized methods for scoring REM sleep without atonia; (4) consistent methods to analyze video and audio recorded during v-PSGs and to classify movements and vocalizations; (5) clear v-PSG guidelines to diagnose RBD and identify prodromal RBD. Each section follows a common template: The current recommendations and methods are presented, their limitations are outlined, and new recommendations are described. Finally, future directions are presented. These v-PSG recommendations are intended for both practicing clinicians and researchers. Classification and quantification of motor events, RBD episodes, and vocalizations are however intended for research purposes only. These v-PSG guidelines will allow collection of homogeneous data, providing objective v-PSG measures and making future harmonized multicentric studies and clinical trials possible.

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