Napping behavior in adults with episodic migraine: a six-week prospective cohort study

Sleep

article

Vgontzas, Angeliki¹  Mostofsky, Elizabeth³  Hagan, Kobina³  Rueschman, Michael⁵  Mittleman, Murray A²  Bertisch, Suzanne M² 

[1] Department of Neurology, Brigham and Women’s Hospital;Harvard Medical School;Department of Epidemiology, Harvard T.H. Chan School of Public Health;Cardiovascular Epidemiology Research Unit, Beth Israel Deaconess Medical Center;Program in Sleep Medicine Epidemiology, Division of Sleep and Circadian Disorders, Brigham and Women’s Hospital

关键词: napping;    migraine;    sleep;    cohort;   

DOI  :  10.1093/sleep/zsab273

学科分类：生理学

来源: American Academy of Sleep Medicine

【 摘 要 】

Study Objectives Patients with migraine commonly endorse napping as a strategy for headache pain relief, but also experience high rates of sleep disturbance. To elucidate the relationship between napping behavior and migraine, we evaluated the association between napping and headache frequency, severity, and intensity among adults with episodic migraine. We also examined the association between daily napping and that night’s sleep.Methods In this six-week prospective cohort study, 97 adults with episodic migraine completed twice-daily headache and sleep electronic diaries and wore a wrist actigraph. We modeled the associations between napping (yes/no) and headaches with conditional logistic regression and daily napping and nighttime sleep with linear regression.Results Over 4,353 study days, participants reported 1,059 headache days and 389 days with naps. More than 80% of participants napped during the study, with mean nap duration of 76.7 ± 62.4 min. Naps were more likely to occur on day 2 of headache 35/242 (14.5%) than on nonheadache days 279/3294 (8.5%, OR 2.2 [95% CI 1.4, 3.4]). Mean nap onset time (14:40 ± 3.3 h) was later than headache onset (12:48 ± 5.3 h). In adjusted models, napping was associated with an additional 1.1 (95% CI −1.4, 3.6) headache days/month. Naps were not associated with worse self-reported or objective sleep that night.Conclusions Our findings suggest that naps may be an uncommonly used behavioral strategy for prolonged migraine attacks and do not contribute to nightly sleep disturbance. Future studies are needed to examine the acute analgesic effects of daytime napping in patients with migraine.

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