Safety and efficiency of femoral artery access closure using QuikClot Combat Gauze in patients with severe arterial calcification of access sites

Quantitative Imaging in Medicine and Surgery

article

Fan-Chieh Meng¹  Chiu-Yang Lee¹ 

[1] Division of Cardiovascular Surgery, Department of Surgery , Taipei Veterans General Hospital;Institute of Clinical Medicine , National Yang Ming Chiao Tung University

关键词: Ankle-brachial index (ABI);    anterior femoral artery calcification (AFAC);    coronary artery disease (CAD);    computerized tomography angiography (CTA);    peripheral arterial occlusive disease (PAOD);    QuikClot Combat Gauze (QIC);   

DOI  :  10.21037/qims-21-1164

学科分类：外科医学

来源: AME Publications

【 摘 要 】

Background: In order to achieve better hemostasis of puncture holes in the femoral artery (FA) after an endovascular procedure, this study evaluated the effect and safety of manual compression (MC) with QuikClot Combat Gauze (QIC) and with mechanical compression (using a C-clamp) of the common access site, the FA, in patients with peripheral arterial occlusive disease (PAOD) combined with anterior femoral artery calcification (AFAC). Methods: We prospectively reviewed 100 patients receiving either MC with QIC or mechanical compression (control group) after endovascular intervention for PAOD plus AFAC from February 2014 to September 2018 in a single unit, which was assessed using computerized tomography angiography (CTA). Results: The mean time to completion of hemostasis was 30±0 minutes in the control group and 18±2.20 minutes in the QIC group (P<0.001). The time to ambulation of the QIC and control groups was 4.38±0.46 and 4.86±0.30 hours (P<0.001), respectively. Eight (16%) patients in the control group had hematoma, as compared with one patient (2%) in the QIC group (P=0.031), while sixteen (32%) patients in the control group had ecchymosis, as compared with four (8%) in the QIC group (P=0.005). Use of QIC and coronary artery disease (CAD) were identified as independent factors correlated with an increased risk of minor complications. Conclusions: QIC facilitated effective and safe hemostasis in patients with PAOD and AFAC.

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