Formulation and Evaluation of Levetiracetam Matrix Tablet Using Polyethylene Oxides

American Journal of PharmTech Research

article

Y.B Raut¹  A.S. Dubey² 

[1] Department of Pharmaceutics, Gawande College of pharmacy;Department of Pharmaceutics, CSM University

关键词: Levetiracetam;    matrix tablet;    Polyethylene oxides;    PEO coagulant;   

DOI  :  10.46624/ajptr.2019.v9.i4.017

学科分类：药学

来源: American Journal Of Pharmtech Research

【 摘 要 】

The objective of work was to prepare and characterize Levetiracetam matrix tablet using Polyethylene oxides (PEO 301, PEO coagulant and PEO 303) by wet granulation technique using variable concentrations of PEO 301, PEO coagulant and PEO 303. Total 12 formulations were prepared and optimized formulation were evaluated by Differential scanning Calorimetry (DSC), Fourier transform infrared spectroscopy (FTIR) and The results obtained showed that the formulations of Levetiracetam prepared with combination PEO 303 (T10) has controlled release over 12 hrs.

【 授权许可】

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