Bratislava Medical Journal | |
Systemic inflammation in both open-angle and angle-closure glaucoma: role of platelet-to-lymphocyte ratio | |
article | |
M. Karahan1  D. Kilic2  S. Guven2  | |
[1] Dicle University Faculty of Medicine, Department of Ophthalmology;Health Science University, Kayseri City Hospital, Department of Ophthalmology | |
关键词: neutrophil-to-lymphocyte ratio; platelet-to-lymphocyte-ratio; primary open-angle glaucoma; primary angle-closure glaucoma; systemic inflammation; | |
DOI : 10.4149/BLL_2021_005 | |
学科分类:医学(综合) | |
来源: AEPress, s.r.o. | |
【 摘 要 】
AIM: To analyse the effect of systemic inflammatory status in patients with primary open-angle glaucoma (POAG) and primary angle-closure glaucoma (PACG) by calculating platelet-to-lymphocyte ratio (PLR) and neutrophil-to-lymphocyte ratio (NLR). METHODS: This retrospective case-control study included 200 patients with POAG, 22 patients with PACG and 100 healthy subjects. The participants’ white-blood-cell, lymphocyte, neutrophil, and platelet counts were recorded from previous blood assays. NLR and PLR were calculated manually. Results were compared among the groups. RESULTS: Both the POAG and PACG groups had higher platelet counts and PLR values than the control group (p=0.001 and p=0.001; respectively). The difference in NLR between POAG, PACG and control groups was not statistically significant (p=0.076). The POAG group had higher NLR values than the control (p=0.035). CONCLUSION: Both the POAG and the PACG groups exhibited higher platelet and PLR levels than the control. These results indicate a potential role of systemic inflammation in the pathogenesis of POAG and PACG (Tab. 4, Fig. 1, Ref. 35).
【 授权许可】
CC BY
【 预 览 】
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RO202302200001328ZK.pdf | 130KB | download |