In Vitro Whitening Properties and Antioxidative Potentials of The Extracts of Three Melastoma Leaves Species (M. malabathricum, M. hirta and M. decemfidum)

Journal of applied sciences research

article

Nur Fauwizah Azahar¹  Siti Salwa Abd Gani¹  Uswatun Hasanah Zaidan¹  Paiman Bawon⁴  Mohd Izuan Effendi Halmi⁵ 

[1] Halal products Research Institute, Universiti Putra Malaysia;Department of Agriculture Technology, Faculty of Agriculture, Universiti Putra Malaysia;Department of Biochemistry, Faculty of Biotechnology and Biomolecular Sciences, Universiti Putra Malaysia;Department of Forest Production, Faculty of Forestry, Universiti Putra Malaysia;Department of Land Management, Faculty of Agriculture, Universiti Putra Malaysia

关键词: Melastoma;    Antioxidants;    Flavonoid content;    Anthocyanin content;    Tyrosinase inhibition;   

DOI  :  10.22587/jasr.2019.15.3.2

学科分类：社会科学、人文和艺术（综合）

来源: AENSI

【 摘 要 】

The skin whitening and antioxidant properties from plant extract is the key to replace synthetic cosmetic formulation and also to obtain safer source with better biological activities. The present study was designed to investigate the antioxidant and tyrosinase inhibitory activities of the three Melastoma leaves extracts (M. malabathricum, M. Hirta and M. Decemfidum). The antioxidant activity was examined by two different methods namely total anthocyanins content (TAC) and total flavonoid content (TFC). The new findings have shown that all the tested exhibited higher flavonoid content in the range 2.27-5.65 mg/ QE/g of extract and 0.37 – 3.24 mg/g of anthocyanin content. Tyrosinase inhibitory activity was performed with L-DOPA as substrate and from the results, all Melastoma leaves plant exhibited good whitening effects in the range 30.7% -70.1% where M. malabathricum was recorded to show highest level of inhibitory activity. Based on the statistical analysis, there were positive correlation (P<0.05) between antioxidant activity of TFC, TAC and tyrosinase activity. Hence, it can be concluded that all Melastoma plant could be a good source for finding natural active whitening properties and antioxidants potentials for the utilization in cosmeceuticals, medicinal and nutraceuticals applications.

【 授权许可】

Unknown