Calcifying pseudoneoplasms of the neuraxis (CAPNON): The great tumor mimicker

Radiology Case Reports

article

Elena Greco¹  Omar Elmandouh¹  Amit Desai¹  Alok Bhatt¹  Prasanna Vibhute¹  Amit Aggarwal¹ 

[1]Mayo Clinic

关键词: Pseudoneoplasms;    Calcifying;    MRI;    CT;   

DOI  :  10.1016/j.radcr.2022.05.082

学科分类：生物化学工程

来源: University of Washington * Department of Radiology

【 摘 要 】

Calcifying pseudoneoplasms of the neuraxis (CAPNON) are very rare intracranial lesions with less than 50 cases reported in literature. These are non-neoplastic in etiology and despite having unique imaging characteristics, are often misdiagnosed as a neoplastic condition like meningioma, chordoma and gliomas . These do not have any predilection for any age, gender or intracranial location and can be seen in a wide range of age groups. Despite having an imaging overlap with neoplastic conditions, CAPNONs have classic histopathologic findings including chondromyxoid matrix, palisading spindle cells and calcific or ossific metaplasia . As more cases are being described in literature the imaging features are also being better defined. We discuss the clinical, imaging and histopathological findings of 2 cases of CAPNON mimicking posterior fossa meningioma and glial neoplasm.

【 授权许可】

CC BY|CC BY-NC-ND