Concurrent COVID-19 and pneumocystis carinii pneumonia in a patient subsequently found to have underlying hairy cell leukemia

Radiology Case Reports

article

Vahan Moradians¹  Bahareh Shateri Amiri¹  Leyla Bahadorizadeh¹  Milad Gholizadeh Mesgarha¹  Shahrzad Sadeghi¹ 

[1] Department of Pulmonology and Critical Care, Iran University of Medical Sciences

关键词: COVID-19;    SARS-CoV-2;    Pneumocystis carinii;    Pneumocystis Jirovecii;    Infection;    Hairy cell leukemia;    Pneumonia;    Chest CT scan;    Bone marrow;    Flow cytometry;   

DOI  :  10.1016/j.radcr.2022.06.026

学科分类：生物化学工程

来源: University of Washington * Department of Radiology

【 摘 要 】

SARS-CoV-2 infection manifestation has great diversity and it becomes even greater while co-infection occurs or there is a serious underlying disease in an affected patient. In this case report, we present a case of a 71-year-old man who underwent a chest CT scan following the development of fever, weakness, and pulmonary symptoms. Chest CT scan showed segmental consolidation with centrilobular nodular infiltration, ground glass opacifications in the inferior segment of the left upper and lower lobes, and left lung pleural thickening which was atypical for either COVID-19 infection or pneumocystis carinii pneumonia but his SARS-CoV-2 PCR result was positive and he received COVID-19 treatment. His symptoms recurred after a few months with the same chest CT findings and subsequent bronchoalveolar lavage revealed the presence of pneumocystis carinii infection . Consequently, he received cotrimoxazole which caused improvement in symptoms, nonetheless splenomegaly and anemia remained in his clinical and laboratory investigation. Accordingly, bone marrow study and flow cytometry was done and confirmed the previously undiagnosed hairy cell leukemia . This case accentuates the fact that when we face atypical clinical or paraclinical features in a COVID-19 patient, we should explore for coinfection or unknown underlying diseases.

【 授权许可】

CC BY|CC BY-NC-ND