Ovarian clear cell carcinoma arising in a large endometrioma — A case report with pathological correlation and literature review

Radiology Case Reports

article

Eduardo Negrão¹  Beatriz Flor-de-Lima¹  Ana Luísa Duarte¹  Ana Costa Braga¹  Raquel Portugal¹  António J. Madureira¹ 

[1] Department of Radiology, Centro Hospitalar Universitário de São João

关键词: Clear cell carcinoma;    Endometriosis;    Endometrioma;    Ovarian cancer;    Magnetic resonance imaging;    Endometriosis-associated ovarian cancer (EAOC);   

DOI  :  10.1016/j.radcr.2022.05.015

学科分类：生物化学工程

来源: University of Washington * Department of Radiology

【 摘 要 】

Endometriosis-associated ovarian cancer represents the most common form of malignancy associated with this benign disease. It has a better prognosis than most types of ovarian cancer, with endometrioid adenocarcinoma and clear cell carcinoma as the main histological types. Clinical presentation is usually nonspecific and tumor biomarkers can be misleading, since they can also be elevated in the presence of benign ovarian endometriosis. We report a case of a 52-year-old woman with known ovarian and deep pelvic endometriosis, who developed ovarian clear cell carcinoma within a large endometrioma . The imaging findings highlight the key role of magnetic resonance imaging in detecting suspicious features such as loss of the “T2 shading” sign, loss of high T1 signal of an endometrioma, or the presence of mural nodules. Early detection of these malignancies is fundamental for adequate surgical treatment and overall outcome.

【 授权许可】

CC BY|CC BY-NC-ND