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COVID-19 infection and pain in adolescents with sickle cell disease: A case series
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Heidi M. Heyman1  Nicole M. Alberts2  Matthew Rees3  Latika Puri4  Michael J. Frett1  Doralina L. Anghelescu1 
[1] Department of Pediatric Medicine, Division of Anesthesiology, St. Jude Children's Research Hospital;Department of Psychology, Concordia University;Department of Oncology, St. Jude Children's Research Hospital;Department of Hematology, Loma Linda University
关键词: anemia;    chronic pain;    COVID-19;    neuropathic pain;    sickle cell disease;    vaso-occlusive crisis;   
DOI  :  10.1002/jha2.587
来源: Wiley
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【 摘 要 】

Adolescents with sickle cell disease (SCD) have been shown to have pain-related sequelae following COVID-19 infection. In this case series, we discuss five adolescents with SCD and SARS-CoV-2 infection who subsequently developed complex pain circumstances manifested as: (1) increased frequency of acute care visits or admissions for pain; (2) new onset chronic pain; (3) new onset neuropathic pain; (4) escalation in the complexity of pharmacologic therapies; (5) increased use of nonpharmacologic interventions. While more research is needed to fully understand the implications of COVID-19 infection on pain in adolescents with SCD, these cases suggest the presence of a complex relationship.

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