Isolated recurrence of prostate cancer to the anterior urethra 5 years after radiation therapy

IJU Case Reports

article

Shinnosuke Fujiwara¹  Masaru Ishida¹  Eri Arai²  Yuto Baba¹  Tadatsugu Anno¹  Hiroaki Kobayashi¹  Yasumasa Miyazaki¹ 

[1] Department of Urology, Saiseikai Yokohamashi Tobu Hospital;Department of Pathology, Keio University School of Medicine

关键词: adenocarcinoma;    androgen antagonists;    local neoplasms recurrence;    prostatic neoplasms;    urethra;   

DOI  :  10.1002/iju5.12394

学科分类：社会科学、人文和艺术（综合）

来源: Wiley

【 摘 要 】

Introduction Primary or metastatic urethral tumors are extremely rare. However, treatment strategies differ between primary and metastatic tumors. Therefore, establishing an accurate diagnosis is critically needed for initiating timely and appropriate therapy. Case presentation We describe the case of a 79-year-old man with prostate cancer treated with radiotherapy and androgen deprivation therapy. He presented with macroscopic hematuria as a symptom of anterior urethral tumor at follow-up. Endoscopic tumor resection was performed. Hematoxylin and eosin staining showed adenocarcinoma component. Immunohistochemical staining revealed presence of metastatic prostate cancer to the urethra. Conclusion Regarding urethral tumors diagnosis, urologists should consider the possibility of metastasis from prostate cancer and perform immunohistochemical examination for establishing accurate diagnosis. Furthermore, if androgen deprivation therapy fails to suppress symptoms, radiotherapy or urethrectomy might be considered.

【 授权许可】

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