Ankyrin-2 genetic variants: A case of Ankyrin-B syndrome

Annals of noninvasive electrocardiology: the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc

article

Jin Song MD¹  Bryan Richard Sasmita MBBS¹  GuoLan Deng MD¹ 

[1] Department of Cardiology, The First Affiliated Hospital of Chongqing Medical University

关键词: ankyrin 2;    Ankyrin-B syndrome;    genetic mutations;    inherited cardiac arrhythmias;   

DOI  :  10.1111/anec.12933

来源: Wiley

【 摘 要 】

Inherited cardiac arrhythmias (ICA) have become one of the leading causes of sudden cardiac death in people under 40 years old. Variants in the ankyrin-B or ankyrin-2 genes will result in several cardiac arrhythmias ranging from sinus node dysfunction to life-threatening arrhythmias. In this case study, we report a typical ankyrin-2 variant, in which ventricular tachyarrhythmias might be reproduced through exercise or stress tests.

【 授权许可】

Unknown