Development and validation of a risk score for chest pain with suspected non-ST-segment elevation acute coronary syndrome

Annals of noninvasive electrocardiology: the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc

article

Chun-Peng Ma MD¹  Xiao-Li Liu MD²  Jian-Shuang Feng MD¹  Xue-Fei Dong BN¹ 

[1] Department of Cardiology, The First Hospital of Qinhuangdao, Hebei Province;Department of Endocrinology, The First Hospital of Qinhuangdao, Hebei Province

关键词: acute coronary syndrome;    chest pain;    NSTE-ACS;    risk assessment;    risk factors;   

DOI  :  10.1111/anec.12929

来源: Wiley

【 摘 要 】

Objective To investigate a new risk score for acute chest pain with suspected non-ST-segment elevation acute coronary syndrome (NSTE-ACS). Methods Patients who suffered from Chest pain and suspected NSTE-ACS were enrolled as subjects. Predictor variables had been analyzed, and a bootstrap technique was used to evaluate the internal validity of the model, and external validation had been assessed for a prospective cohort study. Results Thousand five hundred and sixty-eight patients had been included in this study. Six predictor variables were found to be significant and were used to develop the model. The C-statistic of the model was 0.83, and internal validation revealed the stability of the model and the absence of over-optimism. Patients were given different triage recommendations, and the risk score was prospectively validated. Conclusions A risk score may be a suitable method for assessing the risk of major adverse cardiac events and aiding patient triage in emergency departments among patients with suspected NSTE-ACS.

【 授权许可】

Unknown