Multiple severe late adverse effects after definitive chemoradiation for locally advanced cervical cancer

Precision Radiation Oncology

article

Calida Marie Danko¹  Linda Jahwa Hong²  Jerry Donald Slater¹ 

[1] Radiation Oncology, Loma Linda University Medical Center;Gynecologic Oncology, Loma Linda University Medical Center

关键词: cervical cancer;    radiation therapy;    radioisotope brachytherapy;    radiation sensitivity;   

DOI  :  10.1002/pro6.1126

学科分类：社会科学、人文和艺术（综合）

来源: Wiley

【 摘 要 】

Concurrent chemoradiation is the standard of care for locally advanced cervical cancer and is commonly associated with mild to moderate toxicities. Severe late complications in multiple organ systems in patients without known patient- or treatment-related risk factors are rare. A 42-year-old woman was treated with definitive chemoradiotherapy with external beam radiotherapy and brachytherapy. She had complete resolution of the disease, with no evidence of recurrence. However, she experienced late morbidity in multiple organ systems due to treatment, likely indicating an increased sensitivity to radiation. This case highlights the need for improvements in the identification of such patients.

【 授权许可】

CC BY|CC BY-NC|CC BY-NC-ND