Reproductive medicine and biology | |
Influence of laparoscopic surgery for endometriosis and its recurrence on perinatal outcomes | |
article | |
Yosuke Ono1  Kyoko Furumura2  Osamu Yoshino3  Hajime Ota1  Yasushi Sasaki2  Takao Hidaka4  Yoshiyuki Fukushi1  Shuji Hirata3  Hideto Yamada5  Shinichiro Wada1  | |
[1] Department of Obstetrics and Gynecology, Teine Keijinkai Hospital;Department of Obstetrics and Gynecology, Tonami General Hospital;Department of Obstetrics and Gynecology, University of Yamanashi;Department of Obstetrics and Gynecology, Kurobe City Hospital;Center for Recurrent Pregnancy Loss, Teine Keijinkai Hospital | |
关键词: endometriosis; laparoscopic surgery; perinatal outcome; placenta previa; pregnancy; | |
DOI : 10.1002/rmb2.12456 | |
学科分类:工业工程学 | |
来源: Wiley | |
【 摘 要 】
Purpose It is unknown whether surgery for endometriosis or recurrence of endometriosis affects obstetric outcomes. Methods A total of 208 pregnant women with a history of endometriosis were analyzed. Patients who had endometriomas >3 cm and no history of laparoscopic surgery for endometriosis were defined as non-surgery group ( n = 60), while those who had a history of surgery for endometriosis ( n = 148) were defined as surgery group. We investigated the obstetric outcomes in 208 patients according to with or without postoperative recurrence of endometriosis and the time from surgery to pregnancy. Results Among 177 cases of on-going pregnancy, in surgery group, there were lower prevalence of placenta previa compared with non-surgery group (8.5% vs. 23.4%; p = 0.020). Subgroup analysis revealed a decreased prevalence of placenta previa in postoperative non-recurrence group (6.0%: p = 0.007) compared with non-surgery (23.4%) and postoperative recurrence group (28.6%). Placenta previa was more prevalent in the patients who got pregnant more than 2 years after surgery (20.0%) than the patients who got pregnant within 2 years (2.4%: p = 0.002). Multivariate analysis revealed that the surgery was associated with a reduction in placenta previa (OR: 0.32, 95% CI [0.11–0.90]; p = 0.032). Conclusions Pregnancy within two years after laparoscopic surgery for endometriosis may reduce placenta previa.
【 授权许可】
CC BY|CC BY-NC|CC BY-NC-ND
【 预 览 】
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