Behavioral, Hormonal, and Serotonergic Responses to Different Restricted Feeding Schedules in Rats

International Journal of Tryptophan Research

article

Cristine Vanz Borges¹  Aline Nunes²  Vladimir Eliodoro Costa³  Ricardo de Oliveira Orsi⁴  Leticia Silva Pereira Basilio⁵  Gean Charles Monteiro⁵  Marcelo Maraschin²  Giuseppina Pace Pereira Lima⁵ 

[1] Health Sciences, Universidade Alto Vale do Rio do Peixe;Plant Morphogenesis and Biochemistry Laboratory, Federal University of Santa Catarina;Stable Isotope Center, Institute of Biosciences, São Paulo State University;Center of Education, Science and Technology in Rational Beekeeping ,(NECTAR), College of Veterinary Medicine and Animal Sciences, São Paulo State University;Department of Chemical and Biological Sciences, Institute of Biosciences, São Paulo State University

关键词: L-tryptophan;    serotonin;    melatonin;    L-dopa;    dopamine;   

DOI  :  10.1177/11786469221102098

学科分类：生理学与病理学

来源: Sage Journals

【 摘 要 】

Honey is a natural product with beneficial properties to health and has different characteristics depending on the region of production and collection, flowering, and climate. The presence of precursor amino acids of- and biogenic amines can be important in metabolomic studies of differentiation and quality of honey. We analyzed 65 honeys from 11 distinct regions of the State of Santa Catarina (Brazil) as to the profile of amino acids and biogenic amines by HPLC. The highest L-tryptophan (Trp), 5-hydroxytryptophan (5-OH-Trp), and tryptamine (Tryp) levels were detected in Cfb climate and harvested in 2019. Although we have found high content of serotonin, dopamine, and L-dopa in Cfb climate, the highest values occurred in honey produced during the summer 2018 and at altitudes above 900 m. Results indicate that the amino acids and biogenic amine levels in honeys are good indicators of origin. These data warrant further investigation on the honey as source of amino acids precursor of serotonin, melatonin, and dopamine, what can guide the choice of food as source of neurotransmitters.

【 授权许可】

CC BY|CC BY-NC