Cystic Pancreatic Lesions Beyond the Guidelines: Can we Make an Evidence-Based Decision Whether to Resect or to Observe?

European Medical Journal Gastroenterology

article

Giovanni Marchegiani¹  Stefano Andrianello¹  Giuseppe Malleo¹  Alex Borin¹  Claudio Bassi¹  Roberto Salvia¹ 

[1] Department of Surgery, Pancreas Institute of Verona University

关键词: Pancreatic cyst;    cystic neoplasm of the pancreas;    intraductal papillary mucinous neoplasms;    mucinous;    serous;    Sendai;    Fukuoka;    guidelines;    pancreatic cancer.;   

DOI  :  10.33590/emjgastroenterol/10314932

学科分类：社会科学、人文和艺术（综合）

来源: European Medical Journal

【 摘 要 】

Pancreatic cystic neoplasms (PCNs) are no longer considered as rare entities because their prevalence in the general population ranges from 3–20%. They are usually asymptomatic, incidentally discovered, and diagnosed in the seventh decade of life. The main clinical concern with regard to PCNs is related to their risk of malignant progression, which is relevant for those PCNs that produce mucin. Since 2006, several sets of international guidelines have proposed algorithms for the management of PCNs, and these have been subsequently validated by several studies. Retrospective review of the literature shows that current treatment of PCNs remains unsatisfactory because the guidelines are based on a low level of evidence. However, the guidelines are able to correctly identify lesions that can be safely followed and, as occurs in vaccination campaigns, they are able to exercise a preventive effect in the general population.

【 授权许可】

CC BY-NC