Impact of COPD or Asthma on the Risk of Atrial Fibrillation: A Systematic Review and Meta-Analysis

Frontiers in Cardiovascular Medicine

article

Zhengbiao Xue¹  Siyu Guo²  Xiao Liu⁴  Jianyong Ma⁵  Wengen Zhu⁶  Yue Zhou⁷  Fuwei Liu²  Jun Luo² 

[1] Department of Critial Care Medicine, The First Affiliated Hosptial of Gannan Medical University;Department of Cardiology, The Affiliated Ganzhou Hospital of Nanchang University;Medical Department, Queen Mary school, Nanchang University;Department of Cardiology, Sun Yat-sen Memorial Hospital of Sun Yat-sen University;Department of Pharmacology and Systems Physiology, University of Cincinnati College of Medicine, Cincinnati;Department of Cardiology, The First Affiliated Hospital of Sun Yat-Sen University;State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University

关键词: chronic obstructive pulmonary disease;    asthma;    atrial fibrillation;    risk factor;    meta-analysis;   

DOI  :  10.3389/fcvm.2022.872446

学科分类：地球科学(综合)

来源: Frontiers

【 摘 要 】

Background: Respiratory diseases related to chronic pulmonary ventilation dysfunction are mainly composed of chronic obstructive pulmonary disease (COPD) and asthma. Our meta-analysis aimed to illustrate the association of COPD or asthma with risk of atrial fibrillation (AF). Methods We systematically searched the databases of the PubMed, Embase, and Cochrane library until December 2021 for studies focusing on the relationship between COPD or asthma and AF risk. Due to the potential heterogeneity across studies, the random-effects model was used to pool the studies. Results Our meta-analysis included 14 studies. Based on the random-effects model, the pooled analysis showed that COPD (risk ratio[RR] = 1.74, 95% confidence interval [CI]: 1.70–1.79) and asthma (RR = 1.08, 95% CI: 1.04–1.12) were significantly associated with an increased risk of AF. The results did not change after each study was excluded. Conclusion Our current data suggested that COPD or asthma with associated with an increased risk of AF.

【 授权许可】

CC BY