Is Thoracic Aortic Diameter an Independent Predictor of Cardiovascular Disease and Mortality? A Narrative Review

Frontiers in Cardiovascular Medicine

article

Marijana Tadic¹  Elisa Gherbesi²  Carla Sala²  Stefano Carugo²  Cesare Cuspidi³ 

[1] Department of Cardiology, University Hospital “Dr. Dragisa Misovic-Dedinje”;Department of Clinical Sciences and Community Health, Fondazione Ospedale Maggiore, IRCCS Policlinico di Milano, University of Milano;Department of Medicine and Surgery, University of Milano-Bicocca

关键词: cardiovascular events;    mortality;    echocardiography;    computed tomography;    aortic diameter;   

DOI  :  10.3389/fcvm.2022.867026

学科分类：地球科学(综合)

来源: Frontiers

【 摘 要 】

Subclinical alterations in cardiac structure and function include a variety of abnormal phenotypes of recognized adverse prognostic values, such as left ventricular hypertrophy (LVH), concentric remodeling, systolic/diastolic dysfunction, left atrial dilatation, and alterations of LV geometry. The excess cardiovascular risk associated with these markers has been documented in multiple clinical settings, such as the general population, hypertensive cohorts, patients with coronary heart disease, diabetes mellitus, chronic heart failure, and chronic kidney disease. On the contrary, the value of aortic root (AR) and ascending aortic diameter in predicting cardiovascular outcomes and all-cause mortality in populations free from overt aortic pathology is still debated. The present review, aimed at pointing out the prognostic implications of thoracic aortic dimensions in populations free from known connective and aortic diseases, suggests that available evidence supporting an association between aortic diameter and cardiovascular events, and all-cause mortality is based on the limited number of studies, conducted with different imaging techniques and definition of the aortic phenotype.

【 授权许可】

CC BY