Interconnected Clinical and Social Risk Factors in Breast Cancer and Heart Failure

Frontiers in Cardiovascular Medicine

article

Arjun Sinha¹  Avni Bavishi²  Elizabeth A. Hibler³  Eric H. Yang⁴  Susmita Parashar⁵  Tochukwu Okwuosa⁶  Jeanne M. DeCara⁷  Sherry-Ann Brown⁸  Avirup Guha⁹  Diego Sadler^1,11  Sadiya S. Khan¹  Sanjiv J. Shah¹  Clyde W. Yancy¹  Nausheen Akhter¹ 

[1] Division of Cardiology, Department of Medicine, Northwestern University Feinberg School of Medicine;Department of Medicine, Northwestern University Feinberg School of Medicine;Department of Preventive Medicine, Division of Cancer Epidemiology and Prevention, Northwestern University Feinberg School of Medicine;UCLA Cardio-Oncology Program, Division of Cardiology, Department of Medicine, University of California;Division of Cardiology, Department of Medicine, Emory University;Division of Cardiology, Department of Medicine, Rush University Medical Center;Section of Cardiology, Department of Medicine, University of Chicago Medicine;Division of Cardiology, Department of Medicine, Medical College of Wisconsin;Cardio-Oncology Program, Division of Cardiology, Medical College of Georgia at Augusta University;Cardio-Oncology Program, Division of Cardiology, The Ohio State University Medical Center;Robert and Suzanne Tomsich Department of Cardiovascular Medicine, Heart, Vascular and Thoracic Institute, Cleveland Clinic Florida

关键词: breast cancer;    heart failure;    risk factors;    social determinants of health;    reverse cardio-oncology;   

DOI  :  10.3389/fcvm.2022.847975

学科分类：地球科学(综合)

来源: Frontiers

【 摘 要 】

Breast cancer and heart failure share several known clinical cardiovascular risk factors, including age, obesity, glucose dysregulation, cholesterol dysregulation, hypertension, atrial fibrillation and inflammation. However, to fully comprehend the complex interplay between risk of breast cancer and heart failure, factors attributed to both biological and social determinants of health must be explored in risk-assessment. There are several social factors that impede implementation of prevention strategies and treatment for breast cancer and heart failure prevention, including socioeconomic status, neighborhood disadvantage, food insecurity, access to healthcare, and social isolation. A comprehensive approach to prevention of both breast cancer and heart failure must include assessment for both traditional clinical risk factors and social determinants of health in patients to address root causes of lifestyle and modifiable risk factors. In this review, we examine clinical and social determinants of health in breast cancer and heart failure that are necessary to consider in the design and implementation of effective prevention strategies that altogether reduce the risk of both chronic diseases.

【 授权许可】

CC BY