Physical Activity in Fontan Patients Relates to Quality of Life and Sleep Quality

Frontiers in Cardiovascular Medicine

article

Alessia Callegari¹  Kathrin Faeth¹  Charlène Pfammatter¹  Ruedi Jung³  Florian Berger¹  Barbara Burkhardt¹  Emanuela R. Valsangiacomo Buechel¹ 

[1] University Children's Hospital Zurich, Pediatric Heart Centre;Children's Research Centre;University of Zurich;Epidemiology, Biostatistics and Prevention Institute

关键词: single ventricle;    Fontan;    physical activity;    quality of life;    sleep quality;   

DOI  :  10.3389/fcvm.2022.915810

学科分类：地球科学(综合)

来源: Frontiers

【 摘 要 】

Background and Aim Fontan patients tend to have reduced physical exercise capacity. This study investigates physical activity (PA) and its relationship to exercise capacity, heart rates, cardiac function, biomarkers, health-related quality of life (HRQoL), and sleep quality. Methods Cardiovascular magnetic resonance (CMR), exercise testing (CPET), 24 h-ECG, and blood samples were prospectively performed in 38 patients, age 13 (11–16) years. PA was assessed by accelerometer during 7 consecutive days. HRQoL was self-assessed with KIDSCREEN-27 and SF-36 according to patients' age; sleep quality with Pediatric Sleep Questionnaire (PSQ) and Pittsburgh Sleep Quality Index (PSQI). Results Daily moderate to vigorous physical activity (MVPA) was in median (IQR) 40 (28–57) mins; 7/38 (18%) patients reached the recommended 60 mins/day of MVPA. MVPA did not correlate with gender, age, single ventricle morphology, time from Fontan, heart rate, ventricular volumes, and ejection fraction at CMR, biomarkers, or CPET. Physical wellbeing ( r = 0.33, p = 0.04), autonomy ( r = 0.39, p = 0.03), and social support ( r = 0.43, p = 0.009) assessed using the KIDSCREEN-27, and both physical ( r = 0.57, p = 0.03) and mental ( r = 0.54, p = 0.04) domains of the SF-36 questionnaire correlated with daily minutes of MVPA. PSQI global sleeping score ( r = −0.7, p = 0.007), and PSQ scales for behavior ( r = −0.36; p = 0.03) correlated with daily minutes of MVPA. Conclusion Only 18% of the Fontan patients meet the recommendation for daily MVPA. Measures of exercise capacity, cardiac function or chronotropic competence are not correlated to daily physical activity. In contrast, HRQoL and sleep quality seem to be associated with regular physical activity.

【 授权许可】

CC BY