The Burden of Osteoarthritis in the Middle East and North Africa Region From 1990 to 2019

Frontiers in Medicine

article

Ali Shamekh¹  Mahasti Alizadeh¹  Seyed Aria Nejadghaderi²  Mark J. M. Sullman⁴  Jay S. Kaufman⁶  Gary S. Collins⁷  Ali-Asghar Kolahi⁹  Saeid Safiri^1,10 

[1] Social Determinants of Health Research Center, Department of Community Medicine, Faculty of Medicine, Tabriz University of Medical Sciences;Research Center for Integrative Medicine in Aging, Aging Research Institute, Tabriz University of Medical Sciences;Systematic Review and Meta-Analysis Expert Group ,(SRMEG), Universal Scientific Education and Research Network;Department of Life and Health Sciences, University of Nicosia;Department of Social Sciences, University of Nicosia;Department of Epidemiology, Biostatistics and Occupational Health, Faculty of Medicine, McGill University;Centre for Statistics in Medicine, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, Botnar Research Centre, University of Oxford;NIHR Oxford Biomedical Research Centre, Oxford University Hospitals NHS Foundation Trust;Social Determinants of Health Research Center, Shahid Beheshti University of Medical Sciences;Connective Tissue Diseases Research Center, Tabriz University of Medical Sciences

关键词: osteoarthritis;    epidemiology;    prevalence;    incidence;    burden;    Eastern Mediterranean;   

DOI  :  10.3389/fmed.2022.881391

学科分类：社会科学、人文和艺术（综合）

来源: Frontiers

【 摘 要 】

Objective We aimed to report the most current data on the prevalence, incidence, and years lived with disability (YLDs) associated with osteoarthritis (OA) for the 21 countries and territories located in the Middle East and North Africa (MENA) region from 1990 to 2019 by age, sex, cause, and sociodemographic index (SDI). Methods Publicly available data from the Global Burden of Disease 2019 study were used to report the OA-related burden. Estimates are reported as counts and age-standardized rates, along with their corresponding 95% uncertainty intervals (UIs). Results In 2019, the age-standardized prevalence of OA in MENA was 5,342.8 per 100,000 (95% UI: 4,815.9–5,907.8), which is 9.3% higher than in 1990 (8.1–10.5%). Similarly, the age-standardized annual incidence of OA per 100,000 was 430.4 (382.2–481.9), demonstrating a 9.4% increase since 1990 (8.3–10.5). OA was the cause of 185.4 (92.8–370.2) age-standardized YLDs per 100,000 in 2019, which was 10% higher than in 1990 (8.7–11.4). Saudi Arabia, Kuwait, and Iran had the highest OA burden in MENA, while Yemen, Afghanistan, and Sudan had the lowest burden. In all MENA countries, OA affected more women than men, had an increasing burden with increased age, and had the highest impact on the knee, hip, and hand joints, respectively. OA was also positively associated with the SDI. Conclusion The burden of OA increased over 1990–2019 in the MENA region. The study emphasizes the importance of early preventative approaches in order to control any future health, economic, and quality of life crises imposed by OA in this region.

【 授权许可】

CC BY