Frontiers in Medicine | |
Corneal Biomechanics Differences Between Chinese and Caucasian Healthy Subjects | |
article | |
Riccardo Vinciguerra1  Robert Herber2  Yan Wang3  Fengju Zhang5  Xingtao Zhou6  Ji Bai7  Keming Yu8  Shihao Chen9  Xuejun Fang1,10  Frederik Raiskup2  Paolo Vinciguerra1,11  | |
[1] Humanitas San Pio X Hospital;Department of Ophthalmology, University Hospital Carl Gustav Carus;Tianjin Eye Hospital, Tianjin Key Laboratory of Ophthalmology and Visual Science, Nankai University Affiliated Eye Hospital;Clinical College of Ophthalmology, Tianjin Medical University;Beijing Tongren Eye Center, Beijing Tongren Hospital, Beijing Ophthalmology and Visual Sciences Key Lab, Capital Medical University;EYE & ENT Hospital of Fudan University;BAI JI Ophthalmology;Zhongshan Ophthalmic Center, Sun Yat-Sen University;Eye Hospital, Wenzhou Medical University;Shenyang Aier Eye Hospital;Department of Biomedical Sciences, Humanitas University;IRCCS Humanitas Research Hospital | |
关键词: biomechanics; cornea; keratoconus; CBI; IOP (intraocular pressure); | |
DOI : 10.3389/fmed.2022.834663 | |
学科分类:社会科学、人文和艺术(综合) | |
来源: Frontiers | |
【 摘 要 】
Purpose The aim of this study was to evaluate the difference between Caucasian and Chinese healthy subjects with regards to Corvis ST dynamic corneal response parameters (DCRs). Methods Two thousand eight hundred and eighty-nine healthy Caucasian and Chinese subjects were included in this multicenter retrospective study. Subsequently, Chinese eyes were matched to Caucasians by age, intraocular pressure (IOP), and Corneal Thickness (CCT) using a case-control matching algorithm. The DCRs assessed were Deformation Amplitude (DA) Applanation 1 velocity (A1v), integrated radius (1/R), deformation amplitude ratio (DAratio), stiffness parameter at applanation 1 (SPA1), ARTh (Ambrósio's Relational Thickness to the horizontal profile), and the novel Stress Strain Index (SSI). Results After age-, CCT-, and IOP- matching, 503 Chinese were assigned to 452 Caucasians participants. Statistical analysis showed a statistical significant difference between Chinese and Caucasian Healthy subjects in the values of SPA1 ( p = 0.008), Arth ( p = 0.008), and SSI ( p 0.05). Conclusion We found significant differences in the values of the DCRs provided by the Corvis ST between Chinese and Caucasian healthy subjects.
【 授权许可】
CC BY
【 预 览 】
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