Comparison of Non-contact Tonometry and Goldmann Applanation Tonometry Measurements in Non-pathologic High Myopia

Frontiers in Medicine

article

Peiyuan Wang¹  Yunhe Song¹  Fengbin Lin¹  Zhenyu Wang¹  Xinbo Gao¹  Weijing Cheng¹  Meiling Chen¹  Yuying Peng¹  Yuhong Liu¹  Xiulan Zhang¹  Shida Chen¹ 

[1] State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Guangdong Provincial Clinical Research Center for Ocular Diseases

关键词: intraocular pressure;    high myopia;    non-contact tonometry;    Goldmann applanation tonometry;    axial length;    central corneal thickness;    corneal curvature;   

DOI  :  10.3389/fmed.2022.819715

学科分类：社会科学、人文和艺术（综合）

来源: Frontiers

【 摘 要 】

Purpose To compare intraocular pressure (IOP) values obtained using Goldmann applanation tonometry (IOP GAT ) and non-contact tonometry (IOP NCT ) in a non-pathologic high myopia population. Methods A total of 720 eyes from 720 Chinese adults with non-pathologic high myopia were enrolled in this cross-sectional study. Demographic and ocular characteristics, including axial length, refractive error, central corneal thickness (CCT), and corneal curvature (CC) were recorded. Each patient was successively treated with IOP NCT and IOP GAT . Univariate and multivariable linear regression analyses were conducted to detect factors associated with IOP NCT and IOP GAT , as well as the measurement difference between the two devices (IOP NCT−GAT ). Results In this non-pathologic high myopia population, the mean IOP NCT and IOP GAT values were 17.60 ± 2.76 mmHg and 13.85 ± 2.43 mmHg, respectively. The IOP measurements of the two devices were significantly correlated ( r = 0.681, P < 0.001), however, IOP NCT overestimated IOP GAT with a mean difference of 3.75 mmHg (95% confidence interval: 3.60–3.91 mmHg). In multivariate regression, IOP NCT was significantly associated with body mass index (standardized β = 0.075, p = 0.033), systolic blood pressure (SBP) (standardized β = 0.170, p < 0.001), and CCT (standardized β = 0.526, p < 0.001). As for IOP GAT , only SBP (standardized β = 0.162, p < 0.001), CCT (standardized β = 0.259, p < 0.001), and CC (standardized β = 0.156, p < 0.001) were significantly correlated. The mean IOP NCT−GAT difference increased with younger age (standardized β = −0.134, p < 0.001), higher body mass index (standardized β = 0.091, p = 0.009), higher SBP (standardized β = 0.074, p = 0.027), thicker CCT (standardized β = 0.506, p < 0.001), and lower IOP GAT (standardized β = −0.409, p < 0.001). Conclusion In the non-pathologic high myopia population, IOP NCT overestimated IOP GAT at 3.75 ± 2.10 mmHg. This study suggests that the difference between the values obtained by the two devices, and their respective influencing factors, should be considered in the clinical evaluation and management of highly myopic populations.

【 授权许可】

CC BY